Epithelial Aryl Hydrocarbon Receptor Protects From Mucus Production by Inhibiting ROS-Triggered NLRP3 Inflammasome in Asthma
BackgroundDespite long-standing recognition in the significance of mucus overproduction in asthma, its etiology remains poorly understood. Muc5ac is a secretory mucin that has been associated with reduced pulmonary function and asthma exacerbations.ObjectivesWe sought to investigate the immunologica...
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Autores principales: | Xinyue Hu, Yingchun Shen, Yilin Zhao, Ji Wang, Xin Zhang, Wei Tu, William Kaufman, Juntao Feng, Peisong Gao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/3fd14cf87caf4b32bf86593efa1e708d |
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