PI3K mutations in breast cancer: prognostic and therapeutic implications

Toru MukoharaCancer Center and Division of Medical Oncology/Hematology, Kobe University Hospital, Kobe, JapanAbstract: The PI3K pathway is the most frequently enhanced oncogenic pathway in breast cancer. Among mechanisms of PI3K enhancement, PIK3CA mutations are most frequently (~30%) observed, alon...

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Bibliographic Details
Main Author: Mukohara T
Format: article
Language:EN
Published: Dove Medical Press 2015
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Online Access:https://doaj.org/article/3fd2933d14fe461bb213d49ef70aed6c
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