Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor

Opsins are G protein-coupled receptors which are activated by light-triggered retinal 11-cis-to-all-trans photoisomerization. Here, the authors report a vertebrate non-visual opsin (Opn5L1) that functions as a Gi-coupled retinal receptor, is deactivated by light and can thermally self-regenerate.

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Autores principales: Keita Sato, Takahiro Yamashita, Hideyo Ohuchi, Atsuko Takeuchi, Hitoshi Gotoh, Katsuhiko Ono, Misao Mizuno, Yasuhisa Mizutani, Sayuri Tomonari, Kazumi Sakai, Yasushi Imamoto, Akimori Wada, Yoshinori Shichida
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3fe70ccf8c3742ffb0bddb9e1628427b
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spelling oai:doaj.org-article:3fe70ccf8c3742ffb0bddb9e1628427b2021-12-02T15:34:07ZOpn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor10.1038/s41467-018-03603-32041-1723https://doaj.org/article/3fe70ccf8c3742ffb0bddb9e1628427b2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03603-3https://doaj.org/toc/2041-1723Opsins are G protein-coupled receptors which are activated by light-triggered retinal 11-cis-to-all-trans photoisomerization. Here, the authors report a vertebrate non-visual opsin (Opn5L1) that functions as a Gi-coupled retinal receptor, is deactivated by light and can thermally self-regenerate.Keita SatoTakahiro YamashitaHideyo OhuchiAtsuko TakeuchiHitoshi GotohKatsuhiko OnoMisao MizunoYasuhisa MizutaniSayuri TomonariKazumi SakaiYasushi ImamotoAkimori WadaYoshinori ShichidaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Keita Sato
Takahiro Yamashita
Hideyo Ohuchi
Atsuko Takeuchi
Hitoshi Gotoh
Katsuhiko Ono
Misao Mizuno
Yasuhisa Mizutani
Sayuri Tomonari
Kazumi Sakai
Yasushi Imamoto
Akimori Wada
Yoshinori Shichida
Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
description Opsins are G protein-coupled receptors which are activated by light-triggered retinal 11-cis-to-all-trans photoisomerization. Here, the authors report a vertebrate non-visual opsin (Opn5L1) that functions as a Gi-coupled retinal receptor, is deactivated by light and can thermally self-regenerate.
format article
author Keita Sato
Takahiro Yamashita
Hideyo Ohuchi
Atsuko Takeuchi
Hitoshi Gotoh
Katsuhiko Ono
Misao Mizuno
Yasuhisa Mizutani
Sayuri Tomonari
Kazumi Sakai
Yasushi Imamoto
Akimori Wada
Yoshinori Shichida
author_facet Keita Sato
Takahiro Yamashita
Hideyo Ohuchi
Atsuko Takeuchi
Hitoshi Gotoh
Katsuhiko Ono
Misao Mizuno
Yasuhisa Mizutani
Sayuri Tomonari
Kazumi Sakai
Yasushi Imamoto
Akimori Wada
Yoshinori Shichida
author_sort Keita Sato
title Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
title_short Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
title_full Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
title_fullStr Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
title_full_unstemmed Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
title_sort opn5l1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3fe70ccf8c3742ffb0bddb9e1628427b
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