Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report

Congenital chylous ascites (CCA) is a rare disease, characterized by accumulation of chyle in the peritoneal cavity in infants <3 months. Respiratory distress and abdominal distension at birth are common presentations of CCA. Treatment of CCA includes abdominal paracentesis, medium-chain triglyce...

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Autores principales:	Nasim Rabiee, Ava Navidi Moghaddam, Naeeme Taslimi Taleghani, Shahrzad Tabatabaee, Farzaneh Palizban, Minoo Fallahi
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Congenital chylous ascites Octreotide Necrotizing enterocolitis Pediatrics RJ1-570 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/3fff297ed9ef451182704ec390bc9372
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spelling	oai:doaj.org-article:3fff297ed9ef451182704ec390bc93722021-12-02T05:01:33ZNecrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report2213-576610.1016/j.epsc.2021.102136https://doaj.org/article/3fff297ed9ef451182704ec390bc93722022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2213576621003572https://doaj.org/toc/2213-5766Congenital chylous ascites (CCA) is a rare disease, characterized by accumulation of chyle in the peritoneal cavity in infants <3 months. Respiratory distress and abdominal distension at birth are common presentations of CCA. Treatment of CCA includes abdominal paracentesis, medium-chain triglyceride (MCT) formula, total parenteral nutrition (TPN), and administration of octreotide. Surgical treatment is considered in case of conservative treatment failure. Octreotide administration leads to a reduction in the flow of chyle and predisposes high-risk infants to necrotizing enterocolitis (NEC). We present a case of CCA in a preterm neonate that developed necrotizing NEC, 2 days after initiation of intravenous octreotide. Despite the immediate cessation of octreotide and surgical and supportive treatment, the infant was expired so we suspect that octreotide was a risk factor for the development of NEC in our patient and this report aims to warn this association and suggest that if octreotide is used in treatment, the patient must be under close monitoring for any signs of NEC.Nasim RabieeAva Navidi MoghaddamNaeeme Taslimi TaleghaniShahrzad TabatabaeeFarzaneh PalizbanMinoo FallahiElsevierarticleCongenital chylous ascitesOctreotideNecrotizing enterocolitisPediatricsRJ1-570SurgeryRD1-811ENJournal of Pediatric Surgery Case Reports, Vol 76, Iss , Pp 102136- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Congenital chylous ascites Octreotide Necrotizing enterocolitis Pediatrics RJ1-570 Surgery RD1-811
spellingShingle	Congenital chylous ascites Octreotide Necrotizing enterocolitis Pediatrics RJ1-570 Surgery RD1-811 Nasim Rabiee Ava Navidi Moghaddam Naeeme Taslimi Taleghani Shahrzad Tabatabaee Farzaneh Palizban Minoo Fallahi Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
description	Congenital chylous ascites (CCA) is a rare disease, characterized by accumulation of chyle in the peritoneal cavity in infants <3 months. Respiratory distress and abdominal distension at birth are common presentations of CCA. Treatment of CCA includes abdominal paracentesis, medium-chain triglyceride (MCT) formula, total parenteral nutrition (TPN), and administration of octreotide. Surgical treatment is considered in case of conservative treatment failure. Octreotide administration leads to a reduction in the flow of chyle and predisposes high-risk infants to necrotizing enterocolitis (NEC). We present a case of CCA in a preterm neonate that developed necrotizing NEC, 2 days after initiation of intravenous octreotide. Despite the immediate cessation of octreotide and surgical and supportive treatment, the infant was expired so we suspect that octreotide was a risk factor for the development of NEC in our patient and this report aims to warn this association and suggest that if octreotide is used in treatment, the patient must be under close monitoring for any signs of NEC.
format	article
author	Nasim Rabiee Ava Navidi Moghaddam Naeeme Taslimi Taleghani Shahrzad Tabatabaee Farzaneh Palizban Minoo Fallahi
author_facet	Nasim Rabiee Ava Navidi Moghaddam Naeeme Taslimi Taleghani Shahrzad Tabatabaee Farzaneh Palizban Minoo Fallahi
author_sort	Nasim Rabiee
title	Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
title_short	Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
title_full	Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
title_fullStr	Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
title_full_unstemmed	Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
title_sort	necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/3fff297ed9ef451182704ec390bc9372
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Necrotizing enterocolitis as a side effect of octreotide in a preterm neonate, a case report

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