Homeostatic maintenance of allele-specific p16 methylation in cancer cells accompanied by dynamic focal methylation and hydroxymethylation.

<h4>Aim</h4>p16 Methylation frequently occurs in carcinogenesis. While it has been hypothesized that the p16 methylation states are dynamically maintained in cancer cells, direct evidence supporting this hypothesis has not been available until now.<h4>Methods</h4>A fusion cel...

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Autores principales: Sisi Qin, Qiang Li, Jing Zhou, Zhao-Jun Liu, Na Su, James Wilson, Zhe-Ming Lu, Dajun Deng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/3fff55feffdb4f06a4d933754f4d9aaf
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