Distinguishing between selective sweeps from standing variation and from a de novo mutation.

An outstanding question in human genetics has been the degree to which adaptation occurs from standing genetic variation or from de novo mutations. Here, we combine several common statistics used to detect selection in an Approximate Bayesian Computation (ABC) framework, with the goal of discriminat...

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Autores principales: Benjamin M Peter, Emilia Huerta-Sanchez, Rasmus Nielsen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/40024da6128b4aaf8a77a605246f1bb8
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