A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors

Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.

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Detalles Bibliográficos
Autores principales: Zhengwen An, Maja Sabalic, Ryan F. Bloomquist, Teresa E. Fowler, Todd Streelman, Paul T Sharpe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/40102341f7d14f738391fd9ab20e471c
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Descripción
Sumario:Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.