A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.
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Nature Portfolio
2018
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oai:doaj.org-article:40102341f7d14f738391fd9ab20e471c2021-12-02T15:34:28ZA quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors10.1038/s41467-017-02785-62041-1723https://doaj.org/article/40102341f7d14f738391fd9ab20e471c2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02785-6https://doaj.org/toc/2041-1723Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.Zhengwen AnMaja SabalicRyan F. BloomquistTeresa E. FowlerTodd StreelmanPaul T SharpeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Zhengwen An Maja Sabalic Ryan F. Bloomquist Teresa E. Fowler Todd Streelman Paul T Sharpe A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
description |
Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration. |
format |
article |
author |
Zhengwen An Maja Sabalic Ryan F. Bloomquist Teresa E. Fowler Todd Streelman Paul T Sharpe |
author_facet |
Zhengwen An Maja Sabalic Ryan F. Bloomquist Teresa E. Fowler Todd Streelman Paul T Sharpe |
author_sort |
Zhengwen An |
title |
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
title_short |
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
title_full |
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
title_fullStr |
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
title_full_unstemmed |
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
title_sort |
quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/40102341f7d14f738391fd9ab20e471c |
work_keys_str_mv |
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1718386833780375552 |