A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors

Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.

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Autores principales: Zhengwen An, Maja Sabalic, Ryan F. Bloomquist, Teresa E. Fowler, Todd Streelman, Paul T Sharpe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/40102341f7d14f738391fd9ab20e471c
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spelling oai:doaj.org-article:40102341f7d14f738391fd9ab20e471c2021-12-02T15:34:28ZA quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors10.1038/s41467-017-02785-62041-1723https://doaj.org/article/40102341f7d14f738391fd9ab20e471c2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02785-6https://doaj.org/toc/2041-1723Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.Zhengwen AnMaja SabalicRyan F. BloomquistTeresa E. FowlerTodd StreelmanPaul T SharpeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhengwen An
Maja Sabalic
Ryan F. Bloomquist
Teresa E. Fowler
Todd Streelman
Paul T Sharpe
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
description Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.
format article
author Zhengwen An
Maja Sabalic
Ryan F. Bloomquist
Teresa E. Fowler
Todd Streelman
Paul T Sharpe
author_facet Zhengwen An
Maja Sabalic
Ryan F. Bloomquist
Teresa E. Fowler
Todd Streelman
Paul T Sharpe
author_sort Zhengwen An
title A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
title_short A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
title_full A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
title_fullStr A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
title_full_unstemmed A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
title_sort quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/40102341f7d14f738391fd9ab20e471c
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