Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status

Introduction: Vitamin D (VD) deficiency is a major public health problem worldwide. In spite of its high prevalence, particularly among elderly people, VD deficiency is still underestimated by many physicians. Increasingly, VD deficiency is associated with several known geriatric syndromes. Methods:...

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Autores principales:	Hasan Kweder, Housam Eidi
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2018
Materias:	furosemide geriatrics vitamin d deficiency Medicine R
Acceso en línea:	https://doaj.org/article/401975a4079a4b8f82bf05888f964b7d
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spelling	oai:doaj.org-article:401975a4079a4b8f82bf05888f964b7d2021-12-02T16:27:07ZVitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status2231-07702249-446410.4103/ajm.AJM_20_18https://doaj.org/article/401975a4079a4b8f82bf05888f964b7d2018-10-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.AJM_20_18https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Introduction: Vitamin D (VD) deficiency is a major public health problem worldwide. In spite of its high prevalence, particularly among elderly people, VD deficiency is still underestimated by many physicians. Increasingly, VD deficiency is associated with several known geriatric syndromes. Methods: The study sample consisted of 125 patients, aged 75 years and older, admitted to the acute geriatric unit. The plausible association between the serum 25-hydroxyvitamin D [25(OH)D] level and patient age, sex, body mass index, renal function, cholecystectomy history, and the prescribed drugs had been investigated. The Fisher's exact test was used to conduct the statistical analysis of data. Results: Surprisingly, furosemide treatment was correlated with normal 25(OH)D levels and an increased incidence of secondary hyperparathyroidism. Unlike the other four parameters mentioned above, our data showed that only the patient sex exhibited a significant association with 25(OH)D level as elderly males suffered from a serious VD deficiency as compared to elderly females. Conclusion: Old age is an independent risk factor for VD deficiency. The supplementary dose of VD should be precisely defined to achieve the optimal serum 25(OH)D level in elderly people. The definition of the normal serum 25(OH)D threshold in elderly furosemide-treated patients is worth of further studies.Hasan KwederHousam EidiThieme Medical and Scientific Publishers Pvt. Ltd.articlefurosemidegeriatricsvitamin d deficiencyMedicineRENAvicenna Journal of Medicine, Vol 8, Iss 04, Pp 139-146 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	furosemide geriatrics vitamin d deficiency Medicine R
spellingShingle	furosemide geriatrics vitamin d deficiency Medicine R Hasan Kweder Housam Eidi Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status
description	Introduction: Vitamin D (VD) deficiency is a major public health problem worldwide. In spite of its high prevalence, particularly among elderly people, VD deficiency is still underestimated by many physicians. Increasingly, VD deficiency is associated with several known geriatric syndromes. Methods: The study sample consisted of 125 patients, aged 75 years and older, admitted to the acute geriatric unit. The plausible association between the serum 25-hydroxyvitamin D [25(OH)D] level and patient age, sex, body mass index, renal function, cholecystectomy history, and the prescribed drugs had been investigated. The Fisher's exact test was used to conduct the statistical analysis of data. Results: Surprisingly, furosemide treatment was correlated with normal 25(OH)D levels and an increased incidence of secondary hyperparathyroidism. Unlike the other four parameters mentioned above, our data showed that only the patient sex exhibited a significant association with 25(OH)D level as elderly males suffered from a serious VD deficiency as compared to elderly females. Conclusion: Old age is an independent risk factor for VD deficiency. The supplementary dose of VD should be precisely defined to achieve the optimal serum 25(OH)D level in elderly people. The definition of the normal serum 25(OH)D threshold in elderly furosemide-treated patients is worth of further studies.
format	article
author	Hasan Kweder Housam Eidi
author_facet	Hasan Kweder Housam Eidi
author_sort	Hasan Kweder
title	Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status
title_short	Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status
title_full	Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status
title_fullStr	Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status
title_full_unstemmed	Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status
title_sort	vitamin d deficiency in elderly: risk factors and drugs impact on vitamin d status
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2018
url	https://doaj.org/article/401975a4079a4b8f82bf05888f964b7d
work_keys_str_mv	AT hasankweder vitaminddeficiencyinelderlyriskfactorsanddrugsimpactonvitamindstatus AT housameidi vitaminddeficiencyinelderlyriskfactorsanddrugsimpactonvitamindstatus
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Vitamin D deficiency in elderly: Risk factors and drugs impact on vitamin D status

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