Dot/Icm Type IVB Secretion System Requirements for <named-content content-type="genus-species">Coxiella burnetii</named-content> Growth in Human Macrophages

ABSTRACT Central to Q fever pathogenesis is replication of the causative agent, Coxiella burnetii, within a phagolysosome-like parasitophorous vacuole (PV) in mononuclear phagocytes. C. burnetii modulates PV biogenesis and other host cell functions, such as apoptotic signaling, presumably via the ac...

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Autores principales: Paul A. Beare, Stacey D. Gilk, Charles L. Larson, Joshua Hill, Christopher M. Stead, Anders Omsland, Diane C. Cockrell, Dale Howe, Daniel E. Voth, Robert A. Heinzen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/4022bdaf348d4cecba9f74370bf03c00
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