Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity.

Discovery of transmission blocking compounds is an important intervention strategy necessary to eliminate and eradicate malaria. To date only a small number of drugs that inhibit gametocyte development and thereby transmission from the mosquito to the human host exist. This limitation is largely due...

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Auteurs principaux: Natalie G Sanders, David J Sullivan, Godfree Mlambo, George Dimopoulos, Abhai K Tripathi
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/4031b496e6fe41e989e99a43b44471b9
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