Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

Physical activity has been linked to lower risks of colorectal and breast cancer. Here, the authors present a Mendelian randomisation analysis supporting a potentially causal relationship between higher physical activity levels and lower risks of breast cancer and colorectal cancer.

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Autores principales:	Nikos Papadimitriou, Niki Dimou, Konstantinos K. Tsilidis, Barbara Banbury, Richard M. Martin, Sarah J. Lewis, Nabila Kazmi, Timothy M. Robinson, Demetrius Albanes, Krasimira Aleksandrova, Sonja I. Berndt, D. Timothy Bishop, Hermann Brenner, Daniel D. Buchanan, Bas Bueno-de-Mesquita, Peter T. Campbell, Sergi Castellví-Bel, Andrew T. Chan, Jenny Chang-Claude, Merete Ellingjord-Dale, Jane C. Figueiredo, Steven J. Gallinger, Graham G. Giles, Edward Giovannucci, Stephen B. Gruber, Andrea Gsur, Jochen Hampe, Heather Hampel, Sophia Harlid, Tabitha A. Harrison, Michael Hoffmeister, John L. Hopper, Li Hsu, José María Huerta, Jeroen R. Huyghe, Mark A. Jenkins, Temitope O. Keku, Tilman Kühn, Carlo La Vecchia, Loic Le Marchand, Christopher I. Li, Li Li, Annika Lindblom, Noralane M. Lindor, Brigid Lynch, Sanford D. Markowitz, Giovanna Masala, Anne M. May, Roger Milne, Evelyn Monninkhof, Lorena Moreno, Victor Moreno, Polly A. Newcomb, Kenneth Offit, Vittorio Perduca, Paul D. P. Pharoah, Elizabeth A. Platz, John D. Potter, Gad Rennert, Elio Riboli, Maria-Jose Sánchez, Stephanie L. Schmit, Robert E. Schoen, Gianluca Severi, Sabina Sieri, Martha L. Slattery, Mingyang Song, Catherine M. Tangen, Stephen N. Thibodeau, Ruth C. Travis, Antonia Trichopoulou, Cornelia M. Ulrich, Franzel J. B. van Duijnhoven, Bethany Van Guelpen, Pavel Vodicka, Emily White, Alicja Wolk, Michael O. Woods, Anna H. Wu, Ulrike Peters, Marc J. Gunter, Neil Murphy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4037fa7ca3bb4f78b294ecfd1dccdb68
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spelling	oai:doaj.org-article:4037fa7ca3bb4f78b294ecfd1dccdb682021-12-02T17:33:15ZPhysical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis10.1038/s41467-020-14389-82041-1723https://doaj.org/article/4037fa7ca3bb4f78b294ecfd1dccdb682020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14389-8https://doaj.org/toc/2041-1723Physical activity has been linked to lower risks of colorectal and breast cancer. Here, the authors present a Mendelian randomisation analysis supporting a potentially causal relationship between higher physical activity levels and lower risks of breast cancer and colorectal cancer.Nikos PapadimitriouNiki DimouKonstantinos K. TsilidisBarbara BanburyRichard M. MartinSarah J. LewisNabila KazmiTimothy M. RobinsonDemetrius AlbanesKrasimira AleksandrovaSonja I. BerndtD. Timothy BishopHermann BrennerDaniel D. BuchananBas Bueno-de-MesquitaPeter T. CampbellSergi Castellví-BelAndrew T. ChanJenny Chang-ClaudeMerete Ellingjord-DaleJane C. FigueiredoSteven J. GallingerGraham G. GilesEdward GiovannucciStephen B. GruberAndrea GsurJochen HampeHeather HampelSophia HarlidTabitha A. HarrisonMichael HoffmeisterJohn L. HopperLi HsuJosé María HuertaJeroen R. HuygheMark A. JenkinsTemitope O. KekuTilman KühnCarlo La VecchiaLoic Le MarchandChristopher I. LiLi LiAnnika LindblomNoralane M. LindorBrigid LynchSanford D. MarkowitzGiovanna MasalaAnne M. MayRoger MilneEvelyn MonninkhofLorena MorenoVictor MorenoPolly A. NewcombKenneth OffitVittorio PerducaPaul D. P. PharoahElizabeth A. PlatzJohn D. PotterGad RennertElio RiboliMaria-Jose SánchezStephanie L. SchmitRobert E. SchoenGianluca SeveriSabina SieriMartha L. SlatteryMingyang SongCatherine M. TangenStephen N. ThibodeauRuth C. TravisAntonia TrichopoulouCornelia M. UlrichFranzel J. B. van DuijnhovenBethany Van GuelpenPavel VodickaEmily WhiteAlicja WolkMichael O. WoodsAnna H. WuUlrike PetersMarc J. GunterNeil MurphyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nikos Papadimitriou Niki Dimou Konstantinos K. Tsilidis Barbara Banbury Richard M. Martin Sarah J. Lewis Nabila Kazmi Timothy M. Robinson Demetrius Albanes Krasimira Aleksandrova Sonja I. Berndt D. Timothy Bishop Hermann Brenner Daniel D. Buchanan Bas Bueno-de-Mesquita Peter T. Campbell Sergi Castellví-Bel Andrew T. Chan Jenny Chang-Claude Merete Ellingjord-Dale Jane C. Figueiredo Steven J. Gallinger Graham G. Giles Edward Giovannucci Stephen B. Gruber Andrea Gsur Jochen Hampe Heather Hampel Sophia Harlid Tabitha A. Harrison Michael Hoffmeister John L. Hopper Li Hsu José María Huerta Jeroen R. Huyghe Mark A. Jenkins Temitope O. Keku Tilman Kühn Carlo La Vecchia Loic Le Marchand Christopher I. Li Li Li Annika Lindblom Noralane M. Lindor Brigid Lynch Sanford D. Markowitz Giovanna Masala Anne M. May Roger Milne Evelyn Monninkhof Lorena Moreno Victor Moreno Polly A. Newcomb Kenneth Offit Vittorio Perduca Paul D. P. Pharoah Elizabeth A. Platz John D. Potter Gad Rennert Elio Riboli Maria-Jose Sánchez Stephanie L. Schmit Robert E. Schoen Gianluca Severi Sabina Sieri Martha L. Slattery Mingyang Song Catherine M. Tangen Stephen N. Thibodeau Ruth C. Travis Antonia Trichopoulou Cornelia M. Ulrich Franzel J. B. van Duijnhoven Bethany Van Guelpen Pavel Vodicka Emily White Alicja Wolk Michael O. Woods Anna H. Wu Ulrike Peters Marc J. Gunter Neil Murphy Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
description	Physical activity has been linked to lower risks of colorectal and breast cancer. Here, the authors present a Mendelian randomisation analysis supporting a potentially causal relationship between higher physical activity levels and lower risks of breast cancer and colorectal cancer.
format	article
author	Nikos Papadimitriou Niki Dimou Konstantinos K. Tsilidis Barbara Banbury Richard M. Martin Sarah J. Lewis Nabila Kazmi Timothy M. Robinson Demetrius Albanes Krasimira Aleksandrova Sonja I. Berndt D. Timothy Bishop Hermann Brenner Daniel D. Buchanan Bas Bueno-de-Mesquita Peter T. Campbell Sergi Castellví-Bel Andrew T. Chan Jenny Chang-Claude Merete Ellingjord-Dale Jane C. Figueiredo Steven J. Gallinger Graham G. Giles Edward Giovannucci Stephen B. Gruber Andrea Gsur Jochen Hampe Heather Hampel Sophia Harlid Tabitha A. Harrison Michael Hoffmeister John L. Hopper Li Hsu José María Huerta Jeroen R. Huyghe Mark A. Jenkins Temitope O. Keku Tilman Kühn Carlo La Vecchia Loic Le Marchand Christopher I. Li Li Li Annika Lindblom Noralane M. Lindor Brigid Lynch Sanford D. Markowitz Giovanna Masala Anne M. May Roger Milne Evelyn Monninkhof Lorena Moreno Victor Moreno Polly A. Newcomb Kenneth Offit Vittorio Perduca Paul D. P. Pharoah Elizabeth A. Platz John D. Potter Gad Rennert Elio Riboli Maria-Jose Sánchez Stephanie L. Schmit Robert E. Schoen Gianluca Severi Sabina Sieri Martha L. Slattery Mingyang Song Catherine M. Tangen Stephen N. Thibodeau Ruth C. Travis Antonia Trichopoulou Cornelia M. Ulrich Franzel J. B. van Duijnhoven Bethany Van Guelpen Pavel Vodicka Emily White Alicja Wolk Michael O. Woods Anna H. Wu Ulrike Peters Marc J. Gunter Neil Murphy
author_facet	Nikos Papadimitriou Niki Dimou Konstantinos K. Tsilidis Barbara Banbury Richard M. Martin Sarah J. Lewis Nabila Kazmi Timothy M. Robinson Demetrius Albanes Krasimira Aleksandrova Sonja I. Berndt D. Timothy Bishop Hermann Brenner Daniel D. Buchanan Bas Bueno-de-Mesquita Peter T. Campbell Sergi Castellví-Bel Andrew T. Chan Jenny Chang-Claude Merete Ellingjord-Dale Jane C. Figueiredo Steven J. Gallinger Graham G. Giles Edward Giovannucci Stephen B. Gruber Andrea Gsur Jochen Hampe Heather Hampel Sophia Harlid Tabitha A. Harrison Michael Hoffmeister John L. Hopper Li Hsu José María Huerta Jeroen R. Huyghe Mark A. Jenkins Temitope O. Keku Tilman Kühn Carlo La Vecchia Loic Le Marchand Christopher I. Li Li Li Annika Lindblom Noralane M. Lindor Brigid Lynch Sanford D. Markowitz Giovanna Masala Anne M. May Roger Milne Evelyn Monninkhof Lorena Moreno Victor Moreno Polly A. Newcomb Kenneth Offit Vittorio Perduca Paul D. P. Pharoah Elizabeth A. Platz John D. Potter Gad Rennert Elio Riboli Maria-Jose Sánchez Stephanie L. Schmit Robert E. Schoen Gianluca Severi Sabina Sieri Martha L. Slattery Mingyang Song Catherine M. Tangen Stephen N. Thibodeau Ruth C. Travis Antonia Trichopoulou Cornelia M. Ulrich Franzel J. B. van Duijnhoven Bethany Van Guelpen Pavel Vodicka Emily White Alicja Wolk Michael O. Woods Anna H. Wu Ulrike Peters Marc J. Gunter Neil Murphy
author_sort	Nikos Papadimitriou
title	Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
title_short	Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
title_full	Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
title_fullStr	Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
title_full_unstemmed	Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
title_sort	physical activity and risks of breast and colorectal cancer: a mendelian randomisation analysis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4037fa7ca3bb4f78b294ecfd1dccdb68
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Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

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