CIRCULATING ANTIBODIES TO ERYTHROPOIETIN ARE ASSOCIATED WITH LOWER EFFICACY OF RECOMBINANT EPOETIN TREATMENT IN PATIENTS UNDERGOING HAEMODIALYSIS
Biological preparations (BP) obtained by gene engineering possess a special characteristic called immunogenicity, i.e. propensity of biological drugs to induce an undesired immune response associated with arising anti-drug antibodies. These antibodies can change BP pharmacokinetics and pharmacodynam...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | RU |
| Published: |
SPb RAACI
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/404653d3121049a18d24b7924dea3d80 |
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