Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy

Yiru Wang,* Weiwei Liu,* Kaizheng Chen, Xia Shen Department of Anesthesiology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xia ShenDepartment of Anesthesiology, Eye & ENT Ho...

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Autores principales:	Wang Y, Liu W, Chen K, Shen X
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	laryngeal cancer postoperative delirium activities of daily living outcome Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/4047fecf892548f7958d159ef59a178c
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spelling	oai:doaj.org-article:4047fecf892548f7958d159ef59a178c2021-12-02T17:16:49ZPostoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy1178-1998https://doaj.org/article/4047fecf892548f7958d159ef59a178c2021-05-01T00:00:00Zhttps://www.dovepress.com/postoperative-delirium-is-not-associated-with-long-term-decline-in-act-peer-reviewed-fulltext-article-CIAhttps://doaj.org/toc/1178-1998Yiru Wang,* Weiwei Liu,* Kaizheng Chen, Xia Shen Department of Anesthesiology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xia ShenDepartment of Anesthesiology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, People’s Republic of ChinaTel +8621-643771334Fax +8621-64373416Email zlsx@yahoo.comPurpose: To determine the relationships between postoperative delirium (POD) and postoperative activities of daily living (ADL) and mortality in patients undergoing laryngectomy. We hypothesized that POD would reduce postoperative ADL and increase postoperative mortality.Patients and Methods: The prospective study included older participants (age ≥ 65 y) undergoing total laryngectomy, partial laryngectomy, total laryngectomy plus neck dissection, or partial laryngectomy plus neck dissection under general anesthesia. The diagnosis of delirium was based on the Confusion Assessment Method algorithm, which was administered on postoperative days 1 through 6. ADL were evaluated using the Chinese version of the Index of ADL scale. Follow-up assessments of ADL and mortality were conducted 24 months after surgery.Results: Of 127 participants (aged 70.3 ± 4.1 y), 19 (15.0%) developed POD. POD was not associated with a decrease in ADL after laryngectomy (p=0.599) nor with an increase in postoperative mortality [3/19 (15.8%) vs 12/108 (11.1%), p=0.560, Log rank test]. However, longer surgery duration was significantly associated with worse overall survival (OR, 3.262; 95% CI, 1.261– 9.169, p=0.025).Conclusion: POD was not associated with long-term ADL or mortality after laryngectomy. Prolonged surgery was the only factor associated with a higher postoperative mortality rate.Keywords: laryngeal cancer, postoperative delirium, activities of daily living, outcomeWang YLiu WChen KShen XDove Medical Pressarticlelaryngeal cancerpostoperative deliriumactivities of daily livingoutcomeGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 16, Pp 823-831 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	laryngeal cancer postoperative delirium activities of daily living outcome Geriatrics RC952-954.6
spellingShingle	laryngeal cancer postoperative delirium activities of daily living outcome Geriatrics RC952-954.6 Wang Y Liu W Chen K Shen X Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy
description	Yiru Wang,* Weiwei Liu,* Kaizheng Chen, Xia Shen Department of Anesthesiology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xia ShenDepartment of Anesthesiology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, People’s Republic of ChinaTel +8621-643771334Fax +8621-64373416Email zlsx@yahoo.comPurpose: To determine the relationships between postoperative delirium (POD) and postoperative activities of daily living (ADL) and mortality in patients undergoing laryngectomy. We hypothesized that POD would reduce postoperative ADL and increase postoperative mortality.Patients and Methods: The prospective study included older participants (age ≥ 65 y) undergoing total laryngectomy, partial laryngectomy, total laryngectomy plus neck dissection, or partial laryngectomy plus neck dissection under general anesthesia. The diagnosis of delirium was based on the Confusion Assessment Method algorithm, which was administered on postoperative days 1 through 6. ADL were evaluated using the Chinese version of the Index of ADL scale. Follow-up assessments of ADL and mortality were conducted 24 months after surgery.Results: Of 127 participants (aged 70.3 ± 4.1 y), 19 (15.0%) developed POD. POD was not associated with a decrease in ADL after laryngectomy (p=0.599) nor with an increase in postoperative mortality [3/19 (15.8%) vs 12/108 (11.1%), p=0.560, Log rank test]. However, longer surgery duration was significantly associated with worse overall survival (OR, 3.262; 95% CI, 1.261– 9.169, p=0.025).Conclusion: POD was not associated with long-term ADL or mortality after laryngectomy. Prolonged surgery was the only factor associated with a higher postoperative mortality rate.Keywords: laryngeal cancer, postoperative delirium, activities of daily living, outcome
format	article
author	Wang Y Liu W Chen K Shen X
author_facet	Wang Y Liu W Chen K Shen X
author_sort	Wang Y
title	Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy
title_short	Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy
title_full	Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy
title_fullStr	Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy
title_full_unstemmed	Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy
title_sort	postoperative delirium is not associated with long-term decline in activities of daily living or mortality after laryngectomy
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/4047fecf892548f7958d159ef59a178c
work_keys_str_mv	AT wangy postoperativedeliriumisnotassociatedwithlongtermdeclineinactivitiesofdailylivingormortalityafterlaryngectomy AT liuw postoperativedeliriumisnotassociatedwithlongtermdeclineinactivitiesofdailylivingormortalityafterlaryngectomy AT chenk postoperativedeliriumisnotassociatedwithlongtermdeclineinactivitiesofdailylivingormortalityafterlaryngectomy AT shenx postoperativedeliriumisnotassociatedwithlongtermdeclineinactivitiesofdailylivingormortalityafterlaryngectomy
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Postoperative Delirium is Not Associated with Long-Term Decline in Activities of Daily Living or Mortality After Laryngectomy

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