Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.

Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.

Choroidal neovascularization (CNV) is the common pathological basis of irreversible visual impairment encountered in a variety of chorioretinal diseases; the pathogenesis of its development is complicated and still imperfectly understood. Recent studies indicated that delta-like ligand 4 (Dll4), one...

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Autores principales: Xiao Dong, Yu-Sheng Wang, Guo-Rui Dou, Hui-Yuan Hou, Yuan-Yuan Shi, Rui Zhang, Ke Ma, Lin Wu, Li-Bo Yao, Yan Cai, Jian Zhang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/404b3afbfe414a50ba6b6efc101fccf3
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