LINE-1 transcription in round spermatids is associated with accretion of 5-carboxylcytosine in their open reading frames

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LINE-1 transcription in round spermatids is associated with accretion of 5-carboxylcytosine in their open reading frames

Blythe et al investigate the patterns of oxidized forms of the 5-methylcytosine DNA modification during spermatogenesis. They find that open reading frames of evolutionarily young and transcriptionally active LINE-1 retrotransposons are enriched in 5-carboxylcytosine (5caC) during spermatid maturati...

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Auteurs principaux:	Martin J. Blythe, Ayhan Kocer, Alejandro Rubio-Roldan, Tom Giles, Abdulkadir Abakir, Côme Ialy-Radio, Lee M. Wheldon, Oxana Bereshchenko, Stefano Bruscoli, Alexander Kondrashov, Joël R. Drevet, Richard D. Emes, Andrew D. Johnson, John R. McCarrey, Daniel Gackowski, Ryszard Olinski, Julie Cocquet, Jose L. Garcia-Perez, Alexey Ruzov
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/404f4300a2c74fb1b5b1fc739c852701
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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