Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy

Immunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets.

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Autores principales: Ju Yeon Lee, Hyun Tae Lee, Woori Shin, Jongseok Chae, Jaemo Choi, Sung Hyun Kim, Heejin Lim, Tae Won Heo, Kyeong Young Park, Yeon Ji Lee, Seong Eon Ryu, Ji Young Son, Jee Un Lee, Yong-Seok Heo
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/405043e189914752b01da6da98777da8
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spelling oai:doaj.org-article:405043e189914752b01da6da98777da82021-12-02T14:38:57ZStructural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy10.1038/ncomms133542041-1723https://doaj.org/article/405043e189914752b01da6da98777da82016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13354https://doaj.org/toc/2041-1723Immunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets.Ju Yeon LeeHyun Tae LeeWoori ShinJongseok ChaeJaemo ChoiSung Hyun KimHeejin LimTae Won HeoKyeong Young ParkYeon Ji LeeSeong Eon RyuJi Young SonJee Un LeeYong-Seok HeoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ju Yeon Lee
Hyun Tae Lee
Woori Shin
Jongseok Chae
Jaemo Choi
Sung Hyun Kim
Heejin Lim
Tae Won Heo
Kyeong Young Park
Yeon Ji Lee
Seong Eon Ryu
Ji Young Son
Jee Un Lee
Yong-Seok Heo
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
description Immunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets.
format article
author Ju Yeon Lee
Hyun Tae Lee
Woori Shin
Jongseok Chae
Jaemo Choi
Sung Hyun Kim
Heejin Lim
Tae Won Heo
Kyeong Young Park
Yeon Ji Lee
Seong Eon Ryu
Ji Young Son
Jee Un Lee
Yong-Seok Heo
author_facet Ju Yeon Lee
Hyun Tae Lee
Woori Shin
Jongseok Chae
Jaemo Choi
Sung Hyun Kim
Heejin Lim
Tae Won Heo
Kyeong Young Park
Yeon Ji Lee
Seong Eon Ryu
Ji Young Son
Jee Un Lee
Yong-Seok Heo
author_sort Ju Yeon Lee
title Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
title_short Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
title_full Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
title_fullStr Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
title_full_unstemmed Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
title_sort structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/405043e189914752b01da6da98777da8
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