Wildtype and A30P mutant alpha-synuclein form different fibril structures.

Wildtype and A30P mutant alpha-synuclein form different fibril structures.

Parkinson's Disease (PD) is a neurodegenerative movement disorder affecting millions of people worldwide. One of the key players in the development of the disease is the protein α-synuclein (aSN), which aggregates in the brain of PD patients. The aSN mutant A30P has been reported to cause early...

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Autores principales: Søren Bang Nielsen, Francesca Macchi, Samuele Raccosta, Annette Eva Langkilde, Lise Giehm, Anders Kyrsting, Anna Sigrid Pii Svane, Mauro Manno, Gunna Christiansen, Niels Christian Nielsen, Lene Oddershede, Bente Vestergaard, Daniel Erik Otzen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/40586476b9e64459bf62751891354a2b
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