Wildtype and A30P mutant alpha-synuclein form different fibril structures.

Wildtype and A30P mutant alpha-synuclein form different fibril structures.

Parkinson's Disease (PD) is a neurodegenerative movement disorder affecting millions of people worldwide. One of the key players in the development of the disease is the protein α-synuclein (aSN), which aggregates in the brain of PD patients. The aSN mutant A30P has been reported to cause early...

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Main Authors: Søren Bang Nielsen, Francesca Macchi, Samuele Raccosta, Annette Eva Langkilde, Lise Giehm, Anders Kyrsting, Anna Sigrid Pii Svane, Mauro Manno, Gunna Christiansen, Niels Christian Nielsen, Lene Oddershede, Bente Vestergaard, Daniel Erik Otzen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/40586476b9e64459bf62751891354a2b
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https://doaj.org/article/40586476b9e64459bf62751891354a2b

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