Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment

Understanding the tumour microenvironment is essential for the efficacy of immunotherapies. Here the authors describe the immune landscape in esophageal squamous cell carcinoma and suggest several immunosuppressive mechanisms, which upon targeting may restore anti-tumour immune response.

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Detalles Bibliográficos
Autores principales: Yingxia Zheng, Zheyi Chen, Yichao Han, Li Han, Xin Zou, Bingqian Zhou, Rui Hu, Jie Hao, Shihao Bai, Haibo Xiao, Wei Vivian Li, Alex Bueker, Yanhui Ma, Guohua Xie, Junyao Yang, Shiyu Chen, Hecheng Li, Jian Cao, Lisong Shen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/405b3da8d64045049b0e81729e15379b
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Sumario:Understanding the tumour microenvironment is essential for the efficacy of immunotherapies. Here the authors describe the immune landscape in esophageal squamous cell carcinoma and suggest several immunosuppressive mechanisms, which upon targeting may restore anti-tumour immune response.