Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment

Understanding the tumour microenvironment is essential for the efficacy of immunotherapies. Here the authors describe the immune landscape in esophageal squamous cell carcinoma and suggest several immunosuppressive mechanisms, which upon targeting may restore anti-tumour immune response.

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Autores principales:	Yingxia Zheng, Zheyi Chen, Yichao Han, Li Han, Xin Zou, Bingqian Zhou, Rui Hu, Jie Hao, Shihao Bai, Haibo Xiao, Wei Vivian Li, Alex Bueker, Yanhui Ma, Guohua Xie, Junyao Yang, Shiyu Chen, Hecheng Li, Jian Cao, Lisong Shen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/405b3da8d64045049b0e81729e15379b
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spelling	oai:doaj.org-article:405b3da8d64045049b0e81729e15379b2021-12-02T10:48:19ZImmune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment10.1038/s41467-020-20019-02041-1723https://doaj.org/article/405b3da8d64045049b0e81729e15379b2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20019-0https://doaj.org/toc/2041-1723Understanding the tumour microenvironment is essential for the efficacy of immunotherapies. Here the authors describe the immune landscape in esophageal squamous cell carcinoma and suggest several immunosuppressive mechanisms, which upon targeting may restore anti-tumour immune response.Yingxia ZhengZheyi ChenYichao HanLi HanXin ZouBingqian ZhouRui HuJie HaoShihao BaiHaibo XiaoWei Vivian LiAlex BuekerYanhui MaGuohua XieJunyao YangShiyu ChenHecheng LiJian CaoLisong ShenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yingxia Zheng Zheyi Chen Yichao Han Li Han Xin Zou Bingqian Zhou Rui Hu Jie Hao Shihao Bai Haibo Xiao Wei Vivian Li Alex Bueker Yanhui Ma Guohua Xie Junyao Yang Shiyu Chen Hecheng Li Jian Cao Lisong Shen Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
description	Understanding the tumour microenvironment is essential for the efficacy of immunotherapies. Here the authors describe the immune landscape in esophageal squamous cell carcinoma and suggest several immunosuppressive mechanisms, which upon targeting may restore anti-tumour immune response.
format	article
author	Yingxia Zheng Zheyi Chen Yichao Han Li Han Xin Zou Bingqian Zhou Rui Hu Jie Hao Shihao Bai Haibo Xiao Wei Vivian Li Alex Bueker Yanhui Ma Guohua Xie Junyao Yang Shiyu Chen Hecheng Li Jian Cao Lisong Shen
author_facet	Yingxia Zheng Zheyi Chen Yichao Han Li Han Xin Zou Bingqian Zhou Rui Hu Jie Hao Shihao Bai Haibo Xiao Wei Vivian Li Alex Bueker Yanhui Ma Guohua Xie Junyao Yang Shiyu Chen Hecheng Li Jian Cao Lisong Shen
author_sort	Yingxia Zheng
title	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
title_short	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
title_full	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
title_fullStr	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
title_full_unstemmed	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
title_sort	immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/405b3da8d64045049b0e81729e15379b
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Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment

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