Brain gene expression in a novel mouse model of postpartum mood disorder

Steroid sulfatase (STS) cleaves sulfate groups from steroid hormones; its expression/activity increases in late pregnancy and into the postpartum period. STS-deficient human and mouse mothers display elevated psychopathology and abnormal behaviour respectively; in mice, these effects can be partiall...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Humby Trevor, Davies William
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2019
Materias:	female g-protein coupled receptor mice postpartum depression postpartum psychosis steroid sulfatase Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/405fccdc1ab94ef5bef74917a841cd14
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:405fccdc1ab94ef5bef74917a841cd14
record_format	dspace
spelling	oai:doaj.org-article:405fccdc1ab94ef5bef74917a841cd142021-12-05T14:11:04ZBrain gene expression in a novel mouse model of postpartum mood disorder2081-693610.1515/tnsci-2019-0030https://doaj.org/article/405fccdc1ab94ef5bef74917a841cd142019-08-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2019-0030https://doaj.org/toc/2081-6936Steroid sulfatase (STS) cleaves sulfate groups from steroid hormones; its expression/activity increases in late pregnancy and into the postpartum period. STS-deficient human and mouse mothers display elevated psychopathology and abnormal behaviour respectively; in mice, these effects can be partially normalised by antipsychotic (ziprasidone) administration.Humby TrevorDavies WilliamDe Gruyterarticlefemaleg-protein coupled receptormicepostpartum depressionpostpartum psychosissteroid sulfataseNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 10, Iss 1, Pp 168-174 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	female g-protein coupled receptor mice postpartum depression postpartum psychosis steroid sulfatase Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	female g-protein coupled receptor mice postpartum depression postpartum psychosis steroid sulfatase Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Humby Trevor Davies William Brain gene expression in a novel mouse model of postpartum mood disorder
description	Steroid sulfatase (STS) cleaves sulfate groups from steroid hormones; its expression/activity increases in late pregnancy and into the postpartum period. STS-deficient human and mouse mothers display elevated psychopathology and abnormal behaviour respectively; in mice, these effects can be partially normalised by antipsychotic (ziprasidone) administration.
format	article
author	Humby Trevor Davies William
author_facet	Humby Trevor Davies William
author_sort	Humby Trevor
title	Brain gene expression in a novel mouse model of postpartum mood disorder
title_short	Brain gene expression in a novel mouse model of postpartum mood disorder
title_full	Brain gene expression in a novel mouse model of postpartum mood disorder
title_fullStr	Brain gene expression in a novel mouse model of postpartum mood disorder
title_full_unstemmed	Brain gene expression in a novel mouse model of postpartum mood disorder
title_sort	brain gene expression in a novel mouse model of postpartum mood disorder
publisher	De Gruyter
publishDate	2019
url	https://doaj.org/article/405fccdc1ab94ef5bef74917a841cd14
work_keys_str_mv	AT humbytrevor braingeneexpressioninanovelmousemodelofpostpartummooddisorder AT davieswilliam braingeneexpressioninanovelmousemodelofpostpartummooddisorder
_version_	1718371416442667008

Brain gene expression in a novel mouse model of postpartum mood disorder

Ejemplares similares