The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum

Introduction: Dermatophytosis or tinea is a disease found in the keratinized tissues caused by dermatophytes. The prolonged use of antifungal drugs has adverse effects on humans. Kesum leaves (Polygonum minus Huds) contains the secondary metabolite properties which can act as anti-fungi. Objective:...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Josephine Johan Liauw, Syarifah Nurulyanti Rizki, Diana Natalia, Mahyarudin Mahyarudin
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Sultan Agung Semarang 2021
Materias:	antifungal ethanol extract of kesum leaves (polygonum minus huds) microsporum gypseum Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4061dadaad684a79af8d13a419a77c58
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4061dadaad684a79af8d13a419a77c58
record_format	dspace
spelling	oai:doaj.org-article:4061dadaad684a79af8d13a419a77c582021-11-25T13:16:54ZThe Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum2085-15452339-093X10.30659/sainsmed.v12i1.4448https://doaj.org/article/4061dadaad684a79af8d13a419a77c582021-05-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/4448https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XIntroduction: Dermatophytosis or tinea is a disease found in the keratinized tissues caused by dermatophytes. The prolonged use of antifungal drugs has adverse effects on humans. Kesum leaves (Polygonum minus Huds) contains the secondary metabolite properties which can act as anti-fungi. Objective: This study aimed to determine the antifungal activity of ethanol extract of kesum leaves in inhibiting the Microsporum gypseum. Methods: Phytochemical analysis was performed using a test tube method and thin layer chromatography. The antifungal activity test used a disc diffusion method with the extract concentrations of 5%, 10%, 20%, 40%, and 80%. Kesum leaves macerated using ethanol 96% solvent. Itraconazole 8µl/disk and DMSO4 were respectively used as positive and negative control. Results: Phytochemical analysis on the ethanol extract of kesum leaves showed the secondary metabolite groups of flavonoids, alkaloids, terpenoids, phenolics, and saponins. Ethanol extract of kesum leaves did not form an inhibitory zone on the growth of Microsporum gypseum. Meanwhile in the positive control, in the form of itraconazole 8 µl/disk, the inhibition zone was formed around the disc with a mean value of 37.5 mm. Conclusion: Ethanol extract of kesum leaves (Polygonum minus Huds) has no antifungal activity against the growth of Microsporum gypseum.Josephine Johan LiauwSyarifah Nurulyanti RizkiDiana NataliaMahyarudin MahyarudinUniversitas Sultan Agung Semarangarticleantifungalethanol extract of kesum leaves (polygonum minus huds)microsporum gypseumMedicine (General)R5-920ENSains Medika, Vol 12, Iss 1, Pp 26-33 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antifungal ethanol extract of kesum leaves (polygonum minus huds) microsporum gypseum Medicine (General) R5-920
spellingShingle	antifungal ethanol extract of kesum leaves (polygonum minus huds) microsporum gypseum Medicine (General) R5-920 Josephine Johan Liauw Syarifah Nurulyanti Rizki Diana Natalia Mahyarudin Mahyarudin The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
description	Introduction: Dermatophytosis or tinea is a disease found in the keratinized tissues caused by dermatophytes. The prolonged use of antifungal drugs has adverse effects on humans. Kesum leaves (Polygonum minus Huds) contains the secondary metabolite properties which can act as anti-fungi. Objective: This study aimed to determine the antifungal activity of ethanol extract of kesum leaves in inhibiting the Microsporum gypseum. Methods: Phytochemical analysis was performed using a test tube method and thin layer chromatography. The antifungal activity test used a disc diffusion method with the extract concentrations of 5%, 10%, 20%, 40%, and 80%. Kesum leaves macerated using ethanol 96% solvent. Itraconazole 8µl/disk and DMSO4 were respectively used as positive and negative control. Results: Phytochemical analysis on the ethanol extract of kesum leaves showed the secondary metabolite groups of flavonoids, alkaloids, terpenoids, phenolics, and saponins. Ethanol extract of kesum leaves did not form an inhibitory zone on the growth of Microsporum gypseum. Meanwhile in the positive control, in the form of itraconazole 8 µl/disk, the inhibition zone was formed around the disc with a mean value of 37.5 mm. Conclusion: Ethanol extract of kesum leaves (Polygonum minus Huds) has no antifungal activity against the growth of Microsporum gypseum.
format	article
author	Josephine Johan Liauw Syarifah Nurulyanti Rizki Diana Natalia Mahyarudin Mahyarudin
author_facet	Josephine Johan Liauw Syarifah Nurulyanti Rizki Diana Natalia Mahyarudin Mahyarudin
author_sort	Josephine Johan Liauw
title	The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
title_short	The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
title_full	The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
title_fullStr	The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
title_full_unstemmed	The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
title_sort	antifungal effect of kesum leaf (polygonum minus huds) in ethanol extract on microsporum gypseum
publisher	Universitas Sultan Agung Semarang
publishDate	2021
url	https://doaj.org/article/4061dadaad684a79af8d13a419a77c58
work_keys_str_mv	AT josephinejohanliauw theantifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT syarifahnurulyantirizki theantifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT diananatalia theantifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT mahyarudinmahyarudin theantifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT josephinejohanliauw antifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT syarifahnurulyantirizki antifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT diananatalia antifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum AT mahyarudinmahyarudin antifungaleffectofkesumleafpolygonumminushudsinethanolextractonmicrosporumgypseum
_version_	1718413491954515968

The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum

Ejemplares similares