Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles

Abstract A new mobility particle analyzer, which has been termed Inverted Drift Tube, has been modeled analytically as well as numerically and proven to be a very capable instrument. The basis for the new design have been the shortcomings of the previous ion mobility spectrometers, in particular (a)...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Minal Nahin, Derek Oberreit, Nobuhiko Fukushima, Carlos Larriba-Andaluz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4065d5ed41d748559c9917c862cb443c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4065d5ed41d748559c9917c862cb443c
record_format	dspace
spelling	oai:doaj.org-article:4065d5ed41d748559c9917c862cb443c2021-12-02T15:05:58ZModeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles10.1038/s41598-017-06448-w2045-2322https://doaj.org/article/4065d5ed41d748559c9917c862cb443c2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06448-whttps://doaj.org/toc/2045-2322Abstract A new mobility particle analyzer, which has been termed Inverted Drift Tube, has been modeled analytically as well as numerically and proven to be a very capable instrument. The basis for the new design have been the shortcomings of the previous ion mobility spectrometers, in particular (a) diffusional broadening which leads to degradation of instrument resolution and (b) inadequate low and fixed resolution (not mobility dependent) for large sizes. To overcome the diffusional broadening and have a mobility based resolution, the IDT uses two varying controllable opposite forces, a flow of gas with velocity v gas , and a linearly increasing electric field that opposes the movement. A new parameter, the separation ratio Λ = v drift /v gas , is employed to determine the best possible separation for a given set of nanoparticles. Due to the system’s need to operate at room pressure, two methods of capturing the ions at the end of the drift tube have been developed, Intermittent Push Flow for a large range of mobilities, and Nearly-Stopping Potential Separation, with very high separation but limited only to a narrow mobility range. A chromatography existing concept of resolving power is used to differentiate between peak resolution in the IDT and acceptable separation between similar mobility sizes.Minal NahinDerek OberreitNobuhiko FukushimaCarlos Larriba-AndaluzNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Minal Nahin Derek Oberreit Nobuhiko Fukushima Carlos Larriba-Andaluz Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles
description	Abstract A new mobility particle analyzer, which has been termed Inverted Drift Tube, has been modeled analytically as well as numerically and proven to be a very capable instrument. The basis for the new design have been the shortcomings of the previous ion mobility spectrometers, in particular (a) diffusional broadening which leads to degradation of instrument resolution and (b) inadequate low and fixed resolution (not mobility dependent) for large sizes. To overcome the diffusional broadening and have a mobility based resolution, the IDT uses two varying controllable opposite forces, a flow of gas with velocity v gas , and a linearly increasing electric field that opposes the movement. A new parameter, the separation ratio Λ = v drift /v gas , is employed to determine the best possible separation for a given set of nanoparticles. Due to the system’s need to operate at room pressure, two methods of capturing the ions at the end of the drift tube have been developed, Intermittent Push Flow for a large range of mobilities, and Nearly-Stopping Potential Separation, with very high separation but limited only to a narrow mobility range. A chromatography existing concept of resolving power is used to differentiate between peak resolution in the IDT and acceptable separation between similar mobility sizes.
format	article
author	Minal Nahin Derek Oberreit Nobuhiko Fukushima Carlos Larriba-Andaluz
author_facet	Minal Nahin Derek Oberreit Nobuhiko Fukushima Carlos Larriba-Andaluz
author_sort	Minal Nahin
title	Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles
title_short	Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles
title_full	Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles
title_fullStr	Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles
title_full_unstemmed	Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles
title_sort	modeling of an inverted drift tube for improved mobility analysis of aerosol particles
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4065d5ed41d748559c9917c862cb443c
work_keys_str_mv	AT minalnahin modelingofaninverteddrifttubeforimprovedmobilityanalysisofaerosolparticles AT derekoberreit modelingofaninverteddrifttubeforimprovedmobilityanalysisofaerosolparticles AT nobuhikofukushima modelingofaninverteddrifttubeforimprovedmobilityanalysisofaerosolparticles AT carloslarribaandaluz modelingofaninverteddrifttubeforimprovedmobilityanalysisofaerosolparticles
_version_	1718388639767986176

Modeling of an Inverted Drift Tube for Improved Mobility Analysis of Aerosol Particles

Ejemplares similares