Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients

Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients

Abstract Current standard-of-care treatment of chronically infected hepatitis C virus (HCV) patients involves direct-acting antivirals (DAA). However, concerns exist regarding the emergence of drug -resistant variants and subsequent treatment failure. In this study, we investigate potential natural...

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Autores principales: V. Stalin Raj, Gadissa Bedada Hundie, Anita C. Schürch, Saskia L. Smits, Suzan D. Pas, Sophie Le Pogam, Harry L. A. Janssen, Rob J. de Knegt, Albert D. M. E. Osterhaus, Isabel Najera, Charles A. Boucher, Bart L. Haagmans
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/406c4163dec244f4a42d839b533621dc
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