First Immunoassay for Measuring Isoaspartate in Human Serum Albumin

First Immunoassay for Measuring Isoaspartate in Human Serum Albumin

Isoaspartate (isoAsp) is a damaging amino acid residue formed in proteins mostly as a result of spontaneous deamidation of asparaginyl residues. An association has been found between isoAsp in human serum albumin (HSA) and Alzheimer’s disease (AD). Here we report on a novel monoclonal antibody (mAb)...

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Bibliographic Details
Main Authors: Jijing Wang, Susanna L. Lundström, Sven Seelow, Sergey Rodin, Zhaowei Meng, Juan Astorga-Wells, Qinyu Jia, Roman A. Zubarev
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
in vitro diagnostics
blood analysis
monoclonal antibody (mAb)
mass spectrometry
enzyme-linked immunosorbent assay (ELISA)
human serum albumin (HSA)
Organic chemistry
QD241-441
Online Access:https://doaj.org/article/406db28c57ae42aa81e660866e97c59f
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https://doaj.org/article/406db28c57ae42aa81e660866e97c59f

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