Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies

Chronic obstructive pulmonary disease: Combined inhaler proves effective Results from four in-depth studies show that a combined inhaler is very effective for treatment of moderate to severe chronic lung disease. Alleviating the symptoms of chronic obstructive pulmonary disease (COPD), particularly...

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Autores principales:	Gary T. Ferguson, Jill Karpel, Nathan Bennett, Emmanuelle Clerisme-Beaty, Lars Grönke, Florian Voß, Roland Buhl
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Diseases of the respiratory system RC705-779
Acceso en línea:	https://doaj.org/article/406e40dbb4ce42a9aa38295481bd3e25
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spelling	oai:doaj.org-article:406e40dbb4ce42a9aa38295481bd3e252021-12-02T16:19:45ZEffect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies10.1038/s41533-016-0002-x2055-1010https://doaj.org/article/406e40dbb4ce42a9aa38295481bd3e252017-02-01T00:00:00Zhttps://doi.org/10.1038/s41533-016-0002-xhttps://doaj.org/toc/2055-1010Chronic obstructive pulmonary disease: Combined inhaler proves effective Results from four in-depth studies show that a combined inhaler is very effective for treatment of moderate to severe chronic lung disease. Alleviating the symptoms of chronic obstructive pulmonary disease (COPD), particularly sleep disturbance, is crucial to enhancing patients’ quality of life. Gary Ferguson at the Pulmonary Research Institute of Southeast Michigan, together with other scientists across the USA and Germany, analysed data from four large-scale studies to evaluate the efficacy of STIOLTO Respimat, a combination of two bronchodilators—tiotropium, and olodaterol, which tackle airway obstruction and breathlessness, improving long-term lung function. They found that the new drug combination triggered significant improvements in patients’ quality of life and levels of breathlessness. Use of night-time rescue medication in patients on STIOLTO Respimat was considerably reduced. A greater number of patients responded positively to the combined inhaler than to monotherapy.Gary T. FergusonJill KarpelNathan BennettEmmanuelle Clerisme-BeatyLars GrönkeFlorian VoßRoland BuhlNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 27, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the respiratory system RC705-779
spellingShingle	Diseases of the respiratory system RC705-779 Gary T. Ferguson Jill Karpel Nathan Bennett Emmanuelle Clerisme-Beaty Lars Grönke Florian Voß Roland Buhl Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies
description	Chronic obstructive pulmonary disease: Combined inhaler proves effective Results from four in-depth studies show that a combined inhaler is very effective for treatment of moderate to severe chronic lung disease. Alleviating the symptoms of chronic obstructive pulmonary disease (COPD), particularly sleep disturbance, is crucial to enhancing patients’ quality of life. Gary Ferguson at the Pulmonary Research Institute of Southeast Michigan, together with other scientists across the USA and Germany, analysed data from four large-scale studies to evaluate the efficacy of STIOLTO Respimat, a combination of two bronchodilators—tiotropium, and olodaterol, which tackle airway obstruction and breathlessness, improving long-term lung function. They found that the new drug combination triggered significant improvements in patients’ quality of life and levels of breathlessness. Use of night-time rescue medication in patients on STIOLTO Respimat was considerably reduced. A greater number of patients responded positively to the combined inhaler than to monotherapy.
format	article
author	Gary T. Ferguson Jill Karpel Nathan Bennett Emmanuelle Clerisme-Beaty Lars Grönke Florian Voß Roland Buhl
author_facet	Gary T. Ferguson Jill Karpel Nathan Bennett Emmanuelle Clerisme-Beaty Lars Grönke Florian Voß Roland Buhl
author_sort	Gary T. Ferguson
title	Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies
title_short	Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies
title_full	Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies
title_fullStr	Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies
title_full_unstemmed	Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies
title_sort	effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with copd: results from four randomised, double-blind studies
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/406e40dbb4ce42a9aa38295481bd3e25
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Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies

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