A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly progressive dementia. No clinical blood tests are available for diagnosis. The authors identified three miRNAs in whole-blood that are downregulated in sCJD patients, and discriminate sCJD from Alzheimer’s disease patients and healthy controls....

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Bibliographic Details
Main Authors: Penny J. Norsworthy, Andrew G. B. Thompson, Tze H. Mok, Fernando Guntoro, Luke C. Dabin, Akin Nihat, Ross W. Paterson, Jonathan M. Schott, John Collinge, Simon Mead, Emmanuelle A. Viré
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/40732fec2f7f485e8b575e230a89cba5
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Summary:Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly progressive dementia. No clinical blood tests are available for diagnosis. The authors identified three miRNAs in whole-blood that are downregulated in sCJD patients, and discriminate sCJD from Alzheimer’s disease patients and healthy controls.

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