A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly progressive dementia. No clinical blood tests are available for diagnosis. The authors identified three miRNAs in whole-blood that are downregulated in sCJD patients, and discriminate sCJD from Alzheimer’s disease patients and healthy controls....

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Autores principales:	Penny J. Norsworthy, Andrew G. B. Thompson, Tze H. Mok, Fernando Guntoro, Luke C. Dabin, Akin Nihat, Ross W. Paterson, Jonathan M. Schott, John Collinge, Simon Mead, Emmanuelle A. Viré
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/40732fec2f7f485e8b575e230a89cba5
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spelling	oai:doaj.org-article:40732fec2f7f485e8b575e230a89cba52021-12-02T16:36:37ZA blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis10.1038/s41467-020-17655-x2041-1723https://doaj.org/article/40732fec2f7f485e8b575e230a89cba52020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17655-xhttps://doaj.org/toc/2041-1723Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly progressive dementia. No clinical blood tests are available for diagnosis. The authors identified three miRNAs in whole-blood that are downregulated in sCJD patients, and discriminate sCJD from Alzheimer’s disease patients and healthy controls.Penny J. NorsworthyAndrew G. B. ThompsonTze H. MokFernando GuntoroLuke C. DabinAkin NihatRoss W. PatersonJonathan M. SchottJohn CollingeSimon MeadEmmanuelle A. ViréNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Penny J. Norsworthy Andrew G. B. Thompson Tze H. Mok Fernando Guntoro Luke C. Dabin Akin Nihat Ross W. Paterson Jonathan M. Schott John Collinge Simon Mead Emmanuelle A. Viré A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
description	Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly progressive dementia. No clinical blood tests are available for diagnosis. The authors identified three miRNAs in whole-blood that are downregulated in sCJD patients, and discriminate sCJD from Alzheimer’s disease patients and healthy controls.
format	article
author	Penny J. Norsworthy Andrew G. B. Thompson Tze H. Mok Fernando Guntoro Luke C. Dabin Akin Nihat Ross W. Paterson Jonathan M. Schott John Collinge Simon Mead Emmanuelle A. Viré
author_facet	Penny J. Norsworthy Andrew G. B. Thompson Tze H. Mok Fernando Guntoro Luke C. Dabin Akin Nihat Ross W. Paterson Jonathan M. Schott John Collinge Simon Mead Emmanuelle A. Viré
author_sort	Penny J. Norsworthy
title	A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
title_short	A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
title_full	A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
title_fullStr	A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
title_full_unstemmed	A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
title_sort	blood mirna signature associates with sporadic creutzfeldt-jakob disease diagnosis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/40732fec2f7f485e8b575e230a89cba5
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A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

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