Sensory TRP channels contribute differentially to skin inflammation and persistent itch

Sensory TRP channels contribute differentially to skin inflammation and persistent itch

Allergic contact dermatitis is associated both with persistent itch and inflammation, but it is not known if these are mediated by shared signaling pathways. The authors show that persistent itch requires both TRPA1 and TRPV1, while TRPV1 has a protective role against skin inflammation in mice.

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Detalles Bibliográficos
Autores principales: Jing Feng, Pu Yang, Madison R. Mack, Dariia Dryn, Jialie Luo, Xuan Gong, Shenbin Liu, Landon K. Oetjen, Alexander V. Zholos, Zhinan Mei, Shijin Yin, Brian S. Kim, Hongzhen Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/4078181e402a4584941d633042f9add0
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