A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure

Atherosclerosis, myocardial infarction (MI) and heart failure (HF) are the main causes of mortality and morbidity around the globe. New therapies are needed to better manage ischemic heart disease and HF as existing strategies are not curative. Resveratrol is a stilbene polyphenolic compound with fa...

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Autores principales:	Pema Raj, Sijo Joseph Thandapilly, Jeffrey Wigle, Shelley Zieroth, Thomas Netticadan
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	resveratrol atherosclerosis myocardial infarction heart failure Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/407e793447334e0db2b1de53351ea51b
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spelling	oai:doaj.org-article:407e793447334e0db2b1de53351ea51b2021-11-11T18:34:27ZA Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure10.3390/molecules262166001420-3049https://doaj.org/article/407e793447334e0db2b1de53351ea51b2021-10-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6600https://doaj.org/toc/1420-3049Atherosclerosis, myocardial infarction (MI) and heart failure (HF) are the main causes of mortality and morbidity around the globe. New therapies are needed to better manage ischemic heart disease and HF as existing strategies are not curative. Resveratrol is a stilbene polyphenolic compound with favorable biological effects that counter chronic diseases. Current evidence suggests that resveratrol is cardioprotective in animal models of atherosclerosis, ischemic heart disease, and HF. Though clinical studies for resveratrol have been promising, evidence remains inadequate to introduce it to the clinical setting. In this narrative review, we have comprehensively discussed the relevant compelling evidence regarding the efficacy of resveratrol as a new therapeutic agent for the management of atherosclerosis, MI and HF.Pema RajSijo Joseph ThandapillyJeffrey WigleShelley ZierothThomas NetticadanMDPI AGarticleresveratrolatherosclerosismyocardial infarctionheart failureOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6600, p 6600 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	resveratrol atherosclerosis myocardial infarction heart failure Organic chemistry QD241-441
spellingShingle	resveratrol atherosclerosis myocardial infarction heart failure Organic chemistry QD241-441 Pema Raj Sijo Joseph Thandapilly Jeffrey Wigle Shelley Zieroth Thomas Netticadan A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure
description	Atherosclerosis, myocardial infarction (MI) and heart failure (HF) are the main causes of mortality and morbidity around the globe. New therapies are needed to better manage ischemic heart disease and HF as existing strategies are not curative. Resveratrol is a stilbene polyphenolic compound with favorable biological effects that counter chronic diseases. Current evidence suggests that resveratrol is cardioprotective in animal models of atherosclerosis, ischemic heart disease, and HF. Though clinical studies for resveratrol have been promising, evidence remains inadequate to introduce it to the clinical setting. In this narrative review, we have comprehensively discussed the relevant compelling evidence regarding the efficacy of resveratrol as a new therapeutic agent for the management of atherosclerosis, MI and HF.
format	article
author	Pema Raj Sijo Joseph Thandapilly Jeffrey Wigle Shelley Zieroth Thomas Netticadan
author_facet	Pema Raj Sijo Joseph Thandapilly Jeffrey Wigle Shelley Zieroth Thomas Netticadan
author_sort	Pema Raj
title	A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure
title_short	A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure
title_full	A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure
title_fullStr	A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure
title_full_unstemmed	A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure
title_sort	comprehensive analysis of the efficacy of resveratrol in atherosclerotic cardiovascular disease, myocardial infarction and heart failure
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/407e793447334e0db2b1de53351ea51b
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A Comprehensive Analysis of the Efficacy of Resveratrol in Atherosclerotic Cardiovascular Disease, Myocardial Infarction and Heart Failure

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