Multiscale model of hepatitis C virus dynamics in plasma and liver following combination therapy

Abstract This work explores the application of a physiologically structured population (PSP) framework in modeling hepatitis C virus (HCV) kinetics. To do so, a model was developed for the viral RNA load in plasma and liver as observed in 15 patients treated with a combination therapy of pegylated i...

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Autores principales: Xavier Woot de Trixhe, Wojciech Krzyzanski, An Vermeulen, Juan José Perez‐Ruixo
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/408653afc87f4315b2133467334bc8eb
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