SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players

Abstract There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athlete...

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Autores principales:	S. Fikenzer, A. Kogel, C. Pietsch, D. Lavall, St. Stöbe, U. Rudolph, U. Laufs, P. Hepp, A. Hagendorff
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/408b5e0a4ca74f3484c743671db07477
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spelling	oai:doaj.org-article:408b5e0a4ca74f3484c743671db074772021-12-02T19:13:48ZSARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players10.1038/s41598-021-97120-x2045-2322https://doaj.org/article/408b5e0a4ca74f3484c743671db074772021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97120-xhttps://doaj.org/toc/2045-2322Abstract There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athletes. Eight male elite handball players (27 ± 3.5 y) with past SARS-CoV-2 infection were compared with four uninfected teammates (22 ± 2.6 y). Infected athletes were examined 19 ± 7 days after the first positive PCR test. Echocardiographic assessment of the global longitudinal strain under resting conditions was not significantly changed (− 17.7% vs. − 18.1%). However, magnetic resonance imaging showed minor signs of acute inflammation/oedema in all infected athletes (T2-mapping: + 4.1 ms, p = 0.034) without reaching the Lake-Louis criteria. Spiroergometric analysis showed a significant reduction in VO2max (− 292 ml/min, − 7.0%), oxygen pulse (− 2.4 ml/beat, − 10.4%), and respiratory minute volume (VE) (− 18.9 l/min, − 13.8%) in athletes with a history of SARS-CoV2 infection (p < 0.05, respectively). The parameters were unchanged in the uninfected teammates. SARS-CoV2 infection caused impairment of cardiopulmonary performance during physical effort in elite athletes. It seems reasonable to screen athletes after SARS-CoV2 infection with spiroergometry to identify performance limitations and to guide the return to competition.S. FikenzerA. KogelC. PietschD. LavallSt. StöbeU. RudolphU. LaufsP. HeppA. HagendorffNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q S. Fikenzer A. Kogel C. Pietsch D. Lavall St. Stöbe U. Rudolph U. Laufs P. Hepp A. Hagendorff SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
description	Abstract There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athletes. Eight male elite handball players (27 ± 3.5 y) with past SARS-CoV-2 infection were compared with four uninfected teammates (22 ± 2.6 y). Infected athletes were examined 19 ± 7 days after the first positive PCR test. Echocardiographic assessment of the global longitudinal strain under resting conditions was not significantly changed (− 17.7% vs. − 18.1%). However, magnetic resonance imaging showed minor signs of acute inflammation/oedema in all infected athletes (T2-mapping: + 4.1 ms, p = 0.034) without reaching the Lake-Louis criteria. Spiroergometric analysis showed a significant reduction in VO2max (− 292 ml/min, − 7.0%), oxygen pulse (− 2.4 ml/beat, − 10.4%), and respiratory minute volume (VE) (− 18.9 l/min, − 13.8%) in athletes with a history of SARS-CoV2 infection (p < 0.05, respectively). The parameters were unchanged in the uninfected teammates. SARS-CoV2 infection caused impairment of cardiopulmonary performance during physical effort in elite athletes. It seems reasonable to screen athletes after SARS-CoV2 infection with spiroergometry to identify performance limitations and to guide the return to competition.
format	article
author	S. Fikenzer A. Kogel C. Pietsch D. Lavall St. Stöbe U. Rudolph U. Laufs P. Hepp A. Hagendorff
author_facet	S. Fikenzer A. Kogel C. Pietsch D. Lavall St. Stöbe U. Rudolph U. Laufs P. Hepp A. Hagendorff
author_sort	S. Fikenzer
title	SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
title_short	SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
title_full	SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
title_fullStr	SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
title_full_unstemmed	SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
title_sort	sars-cov2 infection: functional and morphological cardiopulmonary changes in elite handball players
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/408b5e0a4ca74f3484c743671db07477
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SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players

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