Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life
Abstract Epigenetic imprinting is important for neurogenesis and brain function. Hippocampal volumes and brain hyperintensities in late life have been associated with early life circumstances. Epigenetic imprinting may underpin these associations. Methylation was measured at 982 sites in 13 imprinte...
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Autores principales: | Marlene Lorgen-Ritchie, Alison D. Murray, Roger Staff, Anne C. Ferguson-Smith, Marcus Richards, Graham W. Horgan, Louise H. Phillips, Gwen Hoad, Chris McNeil, Antonio Ribeiro, Paul Haggarty |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/40a080c1acde4c3bb914d447e8eb9877 |
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