RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates
RNA promotes liquid-liquid phase separation and contributes to the ribonucleoprotein granule assembly. Here the authors employ the protein scaffold ArtiGranule and show the role of intracellular RNA in nucleation and sizing of the phase separated condensates.
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Nature Portfolio
2019
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oai:doaj.org-article:40a67bdf05fb4718a204bdddd64f38ad2021-12-02T17:01:27ZRNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates10.1038/s41467-019-11241-62041-1723https://doaj.org/article/40a67bdf05fb4718a204bdddd64f38ad2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11241-6https://doaj.org/toc/2041-1723RNA promotes liquid-liquid phase separation and contributes to the ribonucleoprotein granule assembly. Here the authors employ the protein scaffold ArtiGranule and show the role of intracellular RNA in nucleation and sizing of the phase separated condensates.Marina Garcia-Jove NavarroShunnichi KashidaRacha ChouaibSylvie SouquereGérard PierronDominique WeilZoher GuerouiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q |
spellingShingle |
Science Q Marina Garcia-Jove Navarro Shunnichi Kashida Racha Chouaib Sylvie Souquere Gérard Pierron Dominique Weil Zoher Gueroui RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates |
description |
RNA promotes liquid-liquid phase separation and contributes to the ribonucleoprotein granule assembly. Here the authors employ the protein scaffold ArtiGranule and show the role of intracellular RNA in nucleation and sizing of the phase separated condensates. |
format |
article |
author |
Marina Garcia-Jove Navarro Shunnichi Kashida Racha Chouaib Sylvie Souquere Gérard Pierron Dominique Weil Zoher Gueroui |
author_facet |
Marina Garcia-Jove Navarro Shunnichi Kashida Racha Chouaib Sylvie Souquere Gérard Pierron Dominique Weil Zoher Gueroui |
author_sort |
Marina Garcia-Jove Navarro |
title |
RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates |
title_short |
RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates |
title_full |
RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates |
title_fullStr |
RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates |
title_full_unstemmed |
RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates |
title_sort |
rna is a critical element for the sizing and the composition of phase-separated rna–protein condensates |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/40a67bdf05fb4718a204bdddd64f38ad |
work_keys_str_mv |
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1718382141261217792 |