RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates
RNA promotes liquid-liquid phase separation and contributes to the ribonucleoprotein granule assembly. Here the authors employ the protein scaffold ArtiGranule and show the role of intracellular RNA in nucleation and sizing of the phase separated condensates.
Guardado en:
Autores principales: | Marina Garcia-Jove Navarro, Shunnichi Kashida, Racha Chouaib, Sylvie Souquere, Gérard Pierron, Dominique Weil, Zoher Gueroui |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/40a67bdf05fb4718a204bdddd64f38ad |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
por: Kaoru R. Komatsu, et al.
Publicado: (2020) -
Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates
por: Adriana Savastano, et al.
Publicado: (2020) -
Lysine/RNA-interactions drive and regulate biomolecular condensation
por: Tina Ukmar-Godec, et al.
Publicado: (2019) -
A computational framework to study sub-cellular RNA localization
por: Aubin Samacoits, et al.
Publicado: (2018) -
Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
por: Ibraheem Alshareedah, et al.
Publicado: (2021)