A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii

Two-pore channels (TPCs) are cation channels that localize to acidic organelles to regulate Ca2+ dependent events. Here, Li et al. characterize a TPC from Toxoplasma gondii(TgTPC) that localizes to the apicoplast, is critical for maintaining its integrity and relevant for Ca2+ uptake from the ER thr...

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Autores principales:	Zhu-Hong Li, Thayer P. King, Lawrence Ayong, Beejan Asady, Xinjiang Cai, Taufiq Rahman, Stephen A. Vella, Isabelle Coppens, Sandip Patel, Silvia N. J. Moreno
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/40af680df6674080819ee06c0c3a8c98
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spelling	oai:doaj.org-article:40af680df6674080819ee06c0c3a8c982021-12-02T19:16:20ZA plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii10.1038/s41467-021-25987-52041-1723https://doaj.org/article/40af680df6674080819ee06c0c3a8c982021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25987-5https://doaj.org/toc/2041-1723Two-pore channels (TPCs) are cation channels that localize to acidic organelles to regulate Ca2+ dependent events. Here, Li et al. characterize a TPC from Toxoplasma gondii(TgTPC) that localizes to the apicoplast, is critical for maintaining its integrity and relevant for Ca2+ uptake from the ER through stabilizing inter-organelle contact.Zhu-Hong LiThayer P. KingLawrence AyongBeejan AsadyXinjiang CaiTaufiq RahmanStephen A. VellaIsabelle CoppensSandip PatelSilvia N. J. MorenoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhu-Hong Li Thayer P. King Lawrence Ayong Beejan Asady Xinjiang Cai Taufiq Rahman Stephen A. Vella Isabelle Coppens Sandip Patel Silvia N. J. Moreno A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
description	Two-pore channels (TPCs) are cation channels that localize to acidic organelles to regulate Ca2+ dependent events. Here, Li et al. characterize a TPC from Toxoplasma gondii(TgTPC) that localizes to the apicoplast, is critical for maintaining its integrity and relevant for Ca2+ uptake from the ER through stabilizing inter-organelle contact.
format	article
author	Zhu-Hong Li Thayer P. King Lawrence Ayong Beejan Asady Xinjiang Cai Taufiq Rahman Stephen A. Vella Isabelle Coppens Sandip Patel Silvia N. J. Moreno
author_facet	Zhu-Hong Li Thayer P. King Lawrence Ayong Beejan Asady Xinjiang Cai Taufiq Rahman Stephen A. Vella Isabelle Coppens Sandip Patel Silvia N. J. Moreno
author_sort	Zhu-Hong Li
title	A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
title_short	A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
title_full	A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
title_fullStr	A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
title_full_unstemmed	A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
title_sort	plastid two-pore channel essential for inter-organelle communication and growth of toxoplasma gondii
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/40af680df6674080819ee06c0c3a8c98
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A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii

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