Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1.
Lysophosphatidic acid (LPA) is an agonist for peroxisome proliferator activated receptor-γ (PPARγ). Although glycerol-3-phosphate acyltransferase-1 (GPAT1) esterifies glycerol-3-phosphate to form LPA, an intermediate in the de novo synthesis of glycerolipids, it has been assumed that LPA synthesized...
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Auteurs principaux: | Cliona M Stapleton, Douglas G Mashek, Shuli Wang, Cynthia A Nagle, Gary W Cline, Philippe Thuillier, Lisa M Leesnitzer, Lei O Li, Julie B Stimmel, Gerald I Shulman, Rosalind A Coleman |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/40afaff6753f40df85ff7c48255f8fe7 |
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