IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium.
Salmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes diarrhea and acute inflammation of the intestinal mucosa. The pro-inflammatory cytokines IL-17A and IL-17F are strongly induced in the infected mucosa but their contribution in driving the tissue inflammation is not underst...
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Main Authors: | Pascal Songhet, Manja Barthel, Till A Röhn, Laurye Van Maele, Delphine Cayet, Jean-Claude Sirard, Martin Bachmann, Manfred Kopf, Wolf-Dietrich Hardt |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Subjects: | |
Online Access: | https://doaj.org/article/40b58373429a4828a167a5798ac77528 |
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