Type-2 innate lymphoid cells control the development of atherosclerosis in mice

Type-2 innate lymphoid cells (ILC2) affect adipose tissue metabolism and function. Here the authors show that the ILC2 are present in para-aortic adipose tissue and represent a major source of IL-5 and IL-13 required for mounting atheroprotective immunity, which can be altered by high fat diet.

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Autores principales:	Stephen A. Newland, Sarajo Mohanta, Marc Clément, Soraya Taleb, Jennifer A. Walker, Meritxell Nus, Andrew P. Sage, Changjun Yin, Desheng Hu, Lauren L. Kitt, Alison J. Finigan, Hans-Reimer Rodewald, Christoph J. Binder, Andrew N. J. McKenzie, Andreas J. Habenicht, Ziad Mallat
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/40b5f6eeef3343c8899a0bd9503d2198
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spelling	oai:doaj.org-article:40b5f6eeef3343c8899a0bd9503d21982021-12-02T15:37:04ZType-2 innate lymphoid cells control the development of atherosclerosis in mice10.1038/ncomms157812041-1723https://doaj.org/article/40b5f6eeef3343c8899a0bd9503d21982017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15781https://doaj.org/toc/2041-1723Type-2 innate lymphoid cells (ILC2) affect adipose tissue metabolism and function. Here the authors show that the ILC2 are present in para-aortic adipose tissue and represent a major source of IL-5 and IL-13 required for mounting atheroprotective immunity, which can be altered by high fat diet.Stephen A. NewlandSarajo MohantaMarc ClémentSoraya TalebJennifer A. WalkerMeritxell NusAndrew P. SageChangjun YinDesheng HuLauren L. KittAlison J. FiniganHans-Reimer RodewaldChristoph J. BinderAndrew N. J. McKenzieAndreas J. HabenichtZiad MallatNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephen A. Newland Sarajo Mohanta Marc Clément Soraya Taleb Jennifer A. Walker Meritxell Nus Andrew P. Sage Changjun Yin Desheng Hu Lauren L. Kitt Alison J. Finigan Hans-Reimer Rodewald Christoph J. Binder Andrew N. J. McKenzie Andreas J. Habenicht Ziad Mallat Type-2 innate lymphoid cells control the development of atherosclerosis in mice
description	Type-2 innate lymphoid cells (ILC2) affect adipose tissue metabolism and function. Here the authors show that the ILC2 are present in para-aortic adipose tissue and represent a major source of IL-5 and IL-13 required for mounting atheroprotective immunity, which can be altered by high fat diet.
format	article
author	Stephen A. Newland Sarajo Mohanta Marc Clément Soraya Taleb Jennifer A. Walker Meritxell Nus Andrew P. Sage Changjun Yin Desheng Hu Lauren L. Kitt Alison J. Finigan Hans-Reimer Rodewald Christoph J. Binder Andrew N. J. McKenzie Andreas J. Habenicht Ziad Mallat
author_facet	Stephen A. Newland Sarajo Mohanta Marc Clément Soraya Taleb Jennifer A. Walker Meritxell Nus Andrew P. Sage Changjun Yin Desheng Hu Lauren L. Kitt Alison J. Finigan Hans-Reimer Rodewald Christoph J. Binder Andrew N. J. McKenzie Andreas J. Habenicht Ziad Mallat
author_sort	Stephen A. Newland
title	Type-2 innate lymphoid cells control the development of atherosclerosis in mice
title_short	Type-2 innate lymphoid cells control the development of atherosclerosis in mice
title_full	Type-2 innate lymphoid cells control the development of atherosclerosis in mice
title_fullStr	Type-2 innate lymphoid cells control the development of atherosclerosis in mice
title_full_unstemmed	Type-2 innate lymphoid cells control the development of atherosclerosis in mice
title_sort	type-2 innate lymphoid cells control the development of atherosclerosis in mice
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/40b5f6eeef3343c8899a0bd9503d2198
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Type-2 innate lymphoid cells control the development of atherosclerosis in mice

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