Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

Immunoglobulin Light Chain Amyloidosis (AL) is the most common systemic amyloidosis occurring in Western countries. Here the authors present the 4.0 Å cryo-EM structure of light chain AL55 fibrils that were isolated from the heart of an AL systemic amyloidosis patient.

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Autores principales:	Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, Cristina Paissoni, Paola Rognoni, Martina Maritan, Francesca Brambilla, Paolo Milani, Pierluigi Mauri, Carlo Camilloni, Giovanni Palladini, Giampaolo Merlini, Stefano Ricagno, Martino Bolognesi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/40c2c81167ec45c9bf6f9207f2cd41b5
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spelling	oai:doaj.org-article:40c2c81167ec45c9bf6f9207f2cd41b52021-12-02T14:38:44ZCryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient10.1038/s41467-019-09133-w2041-1723https://doaj.org/article/40c2c81167ec45c9bf6f9207f2cd41b52019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09133-whttps://doaj.org/toc/2041-1723Immunoglobulin Light Chain Amyloidosis (AL) is the most common systemic amyloidosis occurring in Western countries. Here the authors present the 4.0 Å cryo-EM structure of light chain AL55 fibrils that were isolated from the heart of an AL systemic amyloidosis patient.Paolo SwuecFrancesca LavatelliMasayoshi TasakiCristina PaissoniPaola RognoniMartina MaritanFrancesca BrambillaPaolo MilaniPierluigi MauriCarlo CamilloniGiovanni PalladiniGiampaolo MerliniStefano RicagnoMartino BolognesiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paolo Swuec Francesca Lavatelli Masayoshi Tasaki Cristina Paissoni Paola Rognoni Martina Maritan Francesca Brambilla Paolo Milani Pierluigi Mauri Carlo Camilloni Giovanni Palladini Giampaolo Merlini Stefano Ricagno Martino Bolognesi Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
description	Immunoglobulin Light Chain Amyloidosis (AL) is the most common systemic amyloidosis occurring in Western countries. Here the authors present the 4.0 Å cryo-EM structure of light chain AL55 fibrils that were isolated from the heart of an AL systemic amyloidosis patient.
format	article
author	Paolo Swuec Francesca Lavatelli Masayoshi Tasaki Cristina Paissoni Paola Rognoni Martina Maritan Francesca Brambilla Paolo Milani Pierluigi Mauri Carlo Camilloni Giovanni Palladini Giampaolo Merlini Stefano Ricagno Martino Bolognesi
author_facet	Paolo Swuec Francesca Lavatelli Masayoshi Tasaki Cristina Paissoni Paola Rognoni Martina Maritan Francesca Brambilla Paolo Milani Pierluigi Mauri Carlo Camilloni Giovanni Palladini Giampaolo Merlini Stefano Ricagno Martino Bolognesi
author_sort	Paolo Swuec
title	Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
title_short	Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
title_full	Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
title_fullStr	Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
title_full_unstemmed	Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
title_sort	cryo-em structure of cardiac amyloid fibrils from an immunoglobulin light chain al amyloidosis patient
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/40c2c81167ec45c9bf6f9207f2cd41b5
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Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

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