Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia

Abstract The magneto-thermal effect, which represents the conversion of magnetostatic energy to heat from magnetic materials, has been spotlighted for potential therapeutic usage in hyperthermia treatments. However, the realization of its potential has been challenged owing to the limited heating fr...

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Autores principales:	Jae-Hyeok Lee, Bosung Kim, Yongsub Kim, Sang-Koog Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/40c6bedc7bad423a8ae18c389b3ad82d
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spelling	oai:doaj.org-article:40c6bedc7bad423a8ae18c389b3ad82d2021-12-02T13:19:22ZUltra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia10.1038/s41598-021-84424-12045-2322https://doaj.org/article/40c6bedc7bad423a8ae18c389b3ad82d2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84424-1https://doaj.org/toc/2045-2322Abstract The magneto-thermal effect, which represents the conversion of magnetostatic energy to heat from magnetic materials, has been spotlighted for potential therapeutic usage in hyperthermia treatments. However, the realization of its potential has been challenged owing to the limited heating from the magnetic nanoparticles. Here, we explored a new-concept of magneto-thermal modality marked by low-power-driven, fast resonant spin-excitation followed by consequent energy dissipation, which concept has yet to be realized for current hyperthermia applications. We investigated the effect of spin resonance-mediated heat dissipation using superparamagnetic Fe3O4 nanoparticles and achieved an extraordinary initial temperature increment rate of more than 150 K/s, which is a significant increase in comparison to that for the conventional magnetic heat induction of nanoparticles. This work would offer highly efficient heat generation and precision wireless controllability for realization of magnetic-hyperthermia-based medical treatment.Jae-Hyeok LeeBosung KimYongsub KimSang-Koog KimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jae-Hyeok Lee Bosung Kim Yongsub Kim Sang-Koog Kim Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
description	Abstract The magneto-thermal effect, which represents the conversion of magnetostatic energy to heat from magnetic materials, has been spotlighted for potential therapeutic usage in hyperthermia treatments. However, the realization of its potential has been challenged owing to the limited heating from the magnetic nanoparticles. Here, we explored a new-concept of magneto-thermal modality marked by low-power-driven, fast resonant spin-excitation followed by consequent energy dissipation, which concept has yet to be realized for current hyperthermia applications. We investigated the effect of spin resonance-mediated heat dissipation using superparamagnetic Fe3O4 nanoparticles and achieved an extraordinary initial temperature increment rate of more than 150 K/s, which is a significant increase in comparison to that for the conventional magnetic heat induction of nanoparticles. This work would offer highly efficient heat generation and precision wireless controllability for realization of magnetic-hyperthermia-based medical treatment.
format	article
author	Jae-Hyeok Lee Bosung Kim Yongsub Kim Sang-Koog Kim
author_facet	Jae-Hyeok Lee Bosung Kim Yongsub Kim Sang-Koog Kim
author_sort	Jae-Hyeok Lee
title	Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
title_short	Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
title_full	Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
title_fullStr	Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
title_full_unstemmed	Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
title_sort	ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/40c6bedc7bad423a8ae18c389b3ad82d
work_keys_str_mv	AT jaehyeoklee ultrahighrateoftemperatureincrementfromsuperparamagneticnanoparticlesforhighlyefficienthyperthermia AT bosungkim ultrahighrateoftemperatureincrementfromsuperparamagneticnanoparticlesforhighlyefficienthyperthermia AT yongsubkim ultrahighrateoftemperatureincrementfromsuperparamagneticnanoparticlesforhighlyefficienthyperthermia AT sangkoogkim ultrahighrateoftemperatureincrementfromsuperparamagneticnanoparticlesforhighlyefficienthyperthermia
_version_	1718393266604343296

Ultra-high rate of temperature increment from superparamagnetic nanoparticles for highly efficient hyperthermia

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