EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells
Recent findings have challenged the centrality of epithelial-to-mesenchymal transition (EMT) in promoting tumour progression. Here the authors show that EMT cells can promote breast cancer metastasis by non-cell autonomous activation of the GLI transcriptional program in neighbouring epithelial tumo...
        Saved in:
      
    
                  | Main Authors: | Deepika Neelakantan, Hengbo Zhou, Michael U. J. Oliphant, Xiaomei Zhang, Lukas M. Simon, David M. Henke, Chad A. Shaw, Meng-Fen Wu, Susan G. Hilsenbeck, Lisa D. White, Michael T. Lewis, Heide L. Ford | 
|---|---|
| Format: | article | 
| Language: | EN | 
| Published: | Nature Portfolio    
    
      2017 | 
| Subjects: | |
| Online Access: | https://doaj.org/article/40cf1e9c00f54d94942b4feaef93dd57 | 
| Tags: | Add Tag 
      No Tags, Be the first to tag this record!
   | 
Similar Items
- 
                
        
          Publisher Correction: EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells        
                  
 by: Deepika Neelakantan, et al.
 Published: (2018)
- 
                
        
          Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration        
                  
 by: Hasini Jayatilaka, et al.
 Published: (2017)
- 
                
        
          CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT        
                  
 by: Arindam Chaudhury, et al.
 Published: (2016)
- 
                
        
          Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres        
                  
 by: Jozef Pisko, et al.
 Published: (2021)
- 
                
        
          Paracrine activity of adipose derived stem cells on limbal epithelial stem cells        
                  
 by: Bartosz Sikora, et al.
 Published: (2021)