Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome

Abstract Proteasomes are a critical component of quality control that regulate turnover of short-lived, unfolded, and misfolded proteins. Proteasome activity has been therapeutically targeted and considered as a treatment option for several chronic lung disorders including pulmonary fibrosis. Althou...

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Auteurs principaux: Sneha Sitaraman, Cheng-Lun Na, Li Yang, Alyssa Filuta, James P. Bridges, Timothy E. Weaver
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/40d2d9dc7bbd4a109b5a7e6963055bb1
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