A Ceftazidime-Avibactam-Resistant and Carbapenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Strain Harboring <italic toggle="yes">bla</italic><sub>KPC-14</sub> Isolated in New York City

Código QR

A Ceftazidime-Avibactam-Resistant and Carbapenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Strain Harboring <italic toggle="yes">bla</italic><sub>KPC-14</sub> Isolated in New York City

ABSTRACT Ceftazidime-avibactam is a potent antibiotic combination against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae. Here, we describe a unique ceftazidime-avibactam-resistant and carbapenem-susceptible K. pneumoniae strain harboring a novel blaKPC-14 variant. This strai...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Siqiang Niu, Kalyan D. Chavda, Jie Wei, Chunhong Zou, Steven H. Marshall, Puneet Dhawan, Deqiang Wang, Robert A. Bonomo, Barry N. Kreiswirth, Liang Chen
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	ceftazidime-avibactam carbapenem KPC plasmid antimicrobial resistance selection Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/40e485492bcf413eb8277942167c5e36
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

<italic toggle="yes">Klebsiella pneumoniae</italic> Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering
por: Melissa D. Barnes, et al.
Publicado: (2017)

Analyses of a Ceftazidime-Avibactam-Resistant <italic toggle="yes">Citrobacter freundii</italic> Isolate Carrying <italic toggle="yes">bla</italic><sub>KPC-2</sub> Reveals a Heterogenous Population and Reversible Genotype
por: Mariana Castanheira, et al.
Publicado: (2018)

Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Acute Infection
por: Pavel P. Khil, et al.
Publicado: (2019)

Complete Genome Sequence of a <italic toggle="yes">bla</italic><sub>KPC-2</sub>-Positive <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Strain Isolated from the Effluent of an Urban Sewage Treatment Plant in Japan
por: Tsuyoshi Sekizuka, et al.
Publicado: (2018)

Characterization of a Multidrug-Resistant Porcine <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Sequence Type 11 Strain Coharboring <italic toggle="yes">bla</italic><sub>KPC-2</sub> and <italic toggle="yes">fosA3</italic> on Two Novel Hybrid Plasmids
por: Wanjiang Zhang, et al.
Publicado: (2019)

Ceftazidime/Avibactam-Resistant <i>Klebsiella pneumoniae</i> subsp. <i>pneumoniae</i> Isolates in a Tertiary Italian Hospital: Identification of a New Mutation of the Carbapenemase Type 3 (KPC-3) Gene Conferring Ceftazidime/Avibactam Resistance
por: Carla Fontana, et al.
Publicado: (2021)

Treatment of UTIs Due to <i>Klebsiella pneumoniae</i> Carbapenemase-Producers: How to Use New Antibiotic Drugs? A Narrative Review
por: Caroline Chapelle, et al.
Publicado: (2021)

Antimicrobial activities of ceftazidime/avibactam, ceftolozane/tazobactam, imipenem/relebactam, meropenem/vaborbactam, and comparators against Pseudomonas aeruginosa from patients with skin and soft tissue infections
por: Helio S. Sader, et al.
Publicado: (2021)

Suboptimal drug exposure leads to selection of different subpopulations of ceftazidime-avibactam-resistant Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae in a critically ill patient
por: Paolo Gaibani, et al.
Publicado: (2021)

In-Vitro Selection of Ceftazidime/Avibactam Resistance in OXA-48-Like-Expressing <i>Klebsiella pneumoniae</i>: In-Vitro and In-Vivo Fitness, Genetic Basis and Activities of β-Lactam Plus Novel β-Lactamase Inhibitor or β-Lactam Enhancer Combinations
por: Snehal Palwe, et al.
Publicado: (2021)

In vitro activity of ceftazidime-avibactam against Enterobacterales and Pseudomonas aeruginosa isolates collected in Latin America as part of the ATLAS global surveillance program, 2017–2019
por: James A. Karlowsky, et al.
Publicado: (2021)

Stool Samples of Acute Diarrhea Inpatients as a Reservoir of ST11 Hypervirulent KPC-2-Producing <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>
por: Beiwen Zheng, et al.
Publicado: (2020)

Novel β-Lactamase <italic toggle="yes">bla</italic><sub>ARL</sub> in <named-content content-type="genus-species">Staphylococcus arlettae</named-content>
por: Sabrina N. Andreis, et al.
Publicado: (2017)

In Vitro Activity Comparison of Ceftazidime–Avibactam and Aztreonam–Avibactam Against Bloodstream Infections With Carbapenem-Resistant Organisms in China
por: Wei Yu, et al.
Publicado: (2021)

Colistin- and Carbapenem-Resistant <named-content content-type="genus-species">Escherichia coli</named-content> Harboring <italic toggle="yes">mcr-1</italic> and <italic toggle="yes">bla</italic><sub>NDM-5</sub>, Causing a Complicated Urinary Tract Infection in a Patient from the United States
por: José R. Mediavilla, et al.
Publicado: (2016)

OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs
por: Christopher Fröhlich, et al.
Publicado: (2019)

Novel IncR/IncP6 Hybrid Plasmid pCRE3-KPC Recovered from a Clinical KPC-2-Producing <named-content content-type="genus-species">Citrobacter braakii</named-content> Isolate
por: Dandan Dong, et al.
Publicado: (2020)

Whole-Genome Sequencing of Human Clinical <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates Reveals Misidentification and Misunderstandings of <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>, <named-content content-type="genus-species">Klebsiella variicola</named-content>, and <named-content content-type="genus-species">Klebsiella quasipneumoniae</named-content>
por: S. Wesley Long, et al.
Publicado: (2017)

Genetic Characterization of Plasmid-Borne <italic toggle="yes">bla</italic><sub>OXA-58</sub> in Distinct <named-content content-type="genus-species">Acinetobacter</named-content> Species
por: Adriana P. Matos, et al.
Publicado: (2019)

Clinical and Molecular Description of a High-Copy IncQ1 KPC-2 Plasmid Harbored by the International ST15 <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Clone
por: Willames M. B. S. Martins, et al.
Publicado: (2020)

Dissemination and Stability of the <italic toggle="yes">bla</italic><sub>NDM-5</sub>-Carrying IncX3-Type Plasmid among Multiclonal <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates
por: Wenjun Zhu, et al.
Publicado: (2020)

Relación clonal y detección del gen blaKPC en cepas de Klebsiella pneumoniae resistentes a carbapenémicos, en un hospital de Venezuela
por: Martínez,Dianny, et al.
Publicado: (2016)

CtaM Is Required for Menaquinol Oxidase <italic toggle="yes">aa</italic><sub>3</sub> Function in <named-content content-type="genus-species">Staphylococcus aureus</named-content>
por: Neal D. Hammer, et al.
Publicado: (2016)

Struggle To Survive: the Choir of Target Alteration, Hydrolyzing Enzyme, and Plasmid Expression as a Novel Aztreonam-Avibactam Resistance Mechanism
por: Ke Ma, et al.
Publicado: (2020)

Novel Transporter Required for Biogenesis of <italic toggle="yes">cbb</italic><sub>3</sub>-Type Cytochrome <italic toggle="yes">c</italic> Oxidase in <named-content content-type="genus-species">Rhodobacter capsulatus</named-content>
por: Seda Ekici, et al.
Publicado: (2012)

Ceftazidime Is the Key Diversification and Selection Driver of VIM-Type Carbapenemases
por: Laura Martínez-García, et al.
Publicado: (2018)

The Monte Carlo Simulation of Three Antimicrobials for Empiric Treatment of Adult Bloodstream Infections With Carbapenem-Resistant Enterobacterales in China
por: Dongna Zou, et al.
Publicado: (2021)

Identification of Mutations in the <italic toggle="yes">mrdA</italic> Gene Encoding PBP2 That Reduce Carbapenem and Diazabicyclooctane Susceptibility of <named-content content-type="genus-species">Escherichia coli</named-content> Clinical Isolates with Mutations in <italic toggle="yes">ftsI</italic> (PBP3) and Which Carry <italic toggle="yes">bla</italic><sub>NDM-1</sub>
por: Srijan Ranjitkar, et al.
Publicado: (2019)

Deciphering the Epidemiological Characteristics and Molecular Features of blaKPC–2- or blaNDM–1-Positive Klebsiella pneumoniae Isolates in a Newly Established Hospital
por: Ruifei Chen, et al.
Publicado: (2021)

Identification and Characterization of the Novel Subunit CcoM in the <italic toggle="yes">cbb</italic><sub>3</sub>-Cytochrome <italic toggle="yes">c</italic> Oxidase from <named-content content-type="genus-species">Pseudomonas stutzeri</named-content> ZoBell
por: Martin Kohlstaedt, et al.
Publicado: (2016)

First Report of <italic toggle="yes">bla</italic><sub>VIM-4</sub>- and <italic toggle="yes">mcr-9</italic>-Coharboring <italic toggle="yes">Enterobacter</italic> Species Isolated from a Pediatric Patient
por: Kalyan D. Chavda, et al.
Publicado: (2019)

KPC: Klebsiella pneumoniae carbapenemasa, principal carbapenemasa en enterobacterias
por: Vera-Leiva,Alejandra, et al.
Publicado: (2017)

Reduced Fitness Costs of <italic toggle="yes">mcr-1.2</italic> Compared to Mutated <italic toggle="yes">pmrB</italic> in Isogenic Colistin-Resistant KPC-3-Producing <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>
por: Cesira Giordano, et al.
Publicado: (2019)

Erratum for Kilian and Tettelin, “Identification of Virulence-Associated Properties by Comparative Genome Analysis of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>, <italic toggle="yes">S. pseudopneumoniae</italic>, <named-content content-type="genus-species">S. mitis</named-content>, Three <named-content content-type="genus-species">S. oralis</named-content> Subspecies, and <italic toggle="yes">S. infantis</italic>”
por: Mogens Kilian, et al.
Publicado: (2019)

Comparative Genomics of Enterococci: Variation in <named-content content-type="genus-species">Enterococcus faecalis</named-content>, Clade Structure in <named-content content-type="genus-species">E. faecium</named-content>, and Defining Characteristics of <italic toggle="yes">E</italic>. <italic toggle="yes">gallinarum</italic> and <italic toggle="yes">E</italic>. <italic toggle="yes">casseliflavus</italic>
por: Kelli L. Palmer, et al.
Publicado: (2012)

Dual β-Lactam Combinations Highly Active against <named-content content-type="genus-species">Mycobacterium abscessus</named-content> Complex <italic toggle="yes">In Vitro</italic>
por: R. Pandey, et al.
Publicado: (2019)

H<sub>2</sub>-Independent Growth of the Hydrogenotrophic Methanogen <named-content content-type="genus-species">Methanococcus maripaludis</named-content>
por: Kyle C. Costa, et al.
Publicado: (2013)

Identification of Novel Viruses in <italic toggle="yes">Amblyomma americanum</italic>, <named-content content-type="genus-species">Dermacentor variabilis</named-content>, and <named-content content-type="genus-species">Ixodes scapularis</named-content> Ticks
por: Rafal Tokarz, et al.
Publicado: (2018)

Identification of Virulence-Associated Properties by Comparative Genome Analysis of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>, <named-content content-type="genus-species">S. pseudopneumoniae</named-content>, <named-content content-type="genus-species">S. mitis</named-content>, Three <named-content content-type="genus-species">S. oralis</named-content> Subspecies, and <italic toggle="yes">S. infantis</italic>
por: Mogens Kilian, et al.
Publicado: (2019)

Is <named-content content-type="genus-species">Anopheles gambiae</named-content> a Natural Host of <italic toggle="yes">Wolbachia</italic>?
por: Ewa Chrostek, et al.
Publicado: (2019)