Pertactin contributes to shedding and transmission of Bordetella bronchiseptica.

Whooping cough is resurging in the United States despite high vaccine coverage. The rapid rise of Bordetella pertussis isolates lacking pertactin (PRN), a key vaccine antigen, has led to concerns about vaccine-driven evolution. Previous studies showed that pertactin can mediate binding to mammalian...

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Autores principales: Longhuan Ma, Kalyan K Dewan, Dawn L Taylor-Mulneix, Shannon M Wagner, Bodo Linz, Israel Rivera, Yang Su, Amanda D Caulfield, Uriel Blas-Machado, Eric T Harvill
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/40e4d7026ce34e4a8ba1a80c781334c4
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