Effect of treatment of gestational diabetes mellitus: a systematic review and meta-analysis.
<h4>Objective</h4>To assess the efficacy and safety of treating pregnant women with gestational diabetes mellitus in comparison to usual antenatal care.<h4>Methods</h4>A systematic review and meta-analysis was conducted by including randomized controlled trials comparing any...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2014
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/40ea8b9ce6664758ae0734a007cc4323 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | <h4>Objective</h4>To assess the efficacy and safety of treating pregnant women with gestational diabetes mellitus in comparison to usual antenatal care.<h4>Methods</h4>A systematic review and meta-analysis was conducted by including randomized controlled trials comparing any form of therapeutic intervention in comparison to usual antenatal care. A literature search was conducted using electronic databases together with a hand search of relevant journals and conference proceedings.<h4>Results</h4>Ten studies involving 3,881 patients contributed to meta-analysis. Our results indicated that gestational diabetes mellitus treatment significantly reduced the risk for macrosomia (RR, 0.47; 95% CI, 0.38-0.57), large for gestational age births (RR, 0.55; 95% CI, 0.45-0.67), shoulder dystocia (RR, 0.42; 95% CI, 0.23-0.77) and gestational hypertension (RR, 0.68; 95% CI, 0.53-0.87) without causing any significant increase in the risk for small for gestational age babies. However, no significant difference was observed between the two groups regarding perinatal/neonatal mortality, neonatal hypoglycemia, birth trauma, preterm births, pre-eclampsia, caesarean section and labor induction.<h4>Conclusion</h4>Treating GDM reduces risk for many important adverse pregnancy outcomes and its association with any harm seems unlikely. |
|---|