Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications

Monitoring human health for early detection of disease conditions or health disorders is of major clinical importance for maintaining a healthy life. Sensors are small devices employed for qualitative and quantitative determination of various analytes by monitoring their properties using a certain t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Luminita Fritea, Florin Banica, Traian Octavian Costea, Liviu Moldovan, Luciana Dobjanschi, Mariana Muresan, Simona Cavalu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	metal nanoparticles carbon-based nanomaterials screen-printed electrodes electrochemical (bio)sensors biomedical applications Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
Acceso en línea:	https://doaj.org/article/40f73dadbc774830be930c8b448a760e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:40f73dadbc774830be930c8b448a760e
record_format	dspace
spelling	oai:doaj.org-article:40f73dadbc774830be930c8b448a760e2021-11-11T17:53:18ZMetal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications10.3390/ma142163191996-1944https://doaj.org/article/40f73dadbc774830be930c8b448a760e2021-10-01T00:00:00Zhttps://www.mdpi.com/1996-1944/14/21/6319https://doaj.org/toc/1996-1944Monitoring human health for early detection of disease conditions or health disorders is of major clinical importance for maintaining a healthy life. Sensors are small devices employed for qualitative and quantitative determination of various analytes by monitoring their properties using a certain transduction method. A “real-time” biosensor includes a biological recognition receptor (such as an antibody, enzyme, nucleic acid or whole cell) and a transducer to convert the biological binding event to a detectable signal, which is read out indicating both the presence and concentration of the analyte molecule. A wide range of specific analytes with biomedical significance at ultralow concentration can be sensitively detected. In nano(bio)sensors, nanoparticles (NPs) are incorporated into the (bio)sensor design by attachment to the suitably modified platforms. For this purpose, metal nanoparticles have many advantageous properties making them useful in the transducer component of the (bio)sensors. Gold, silver and platinum NPs have been the most popular ones, each form of these metallic NPs exhibiting special surface and interface features, which significantly improve the biocompatibility and transduction of the (bio)sensor compared to the same process in the absence of these NPs. This comprehensive review is focused on the main types of NPs used for electrochemical (bio)sensors design, especially screen-printed electrodes, with their specific medical application due to their improved analytical performances and miniaturized form. Other advantages such as supporting real-time decision and rapid manipulation are pointed out. A special attention is paid to carbon-based nanomaterials (especially carbon nanotubes and graphene), used by themselves or decorated with metal nanoparticles, with excellent features such as high surface area, excellent conductivity, effective catalytic properties and biocompatibility, which confer to these hybrid nanocomposites a wide biomedical applicability.Luminita FriteaFlorin BanicaTraian Octavian CosteaLiviu MoldovanLuciana DobjanschiMariana MuresanSimona CavaluMDPI AGarticlemetal nanoparticlescarbon-based nanomaterialsscreen-printed electrodeselectrochemical (bio)sensorsbiomedical applicationsTechnologyTElectrical engineering. Electronics. Nuclear engineeringTK1-9971Engineering (General). Civil engineering (General)TA1-2040MicroscopyQH201-278.5Descriptive and experimental mechanicsQC120-168.85ENMaterials, Vol 14, Iss 6319, p 6319 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	metal nanoparticles carbon-based nanomaterials screen-printed electrodes electrochemical (bio)sensors biomedical applications Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
spellingShingle	metal nanoparticles carbon-based nanomaterials screen-printed electrodes electrochemical (bio)sensors biomedical applications Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 Luminita Fritea Florin Banica Traian Octavian Costea Liviu Moldovan Luciana Dobjanschi Mariana Muresan Simona Cavalu Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
description	Monitoring human health for early detection of disease conditions or health disorders is of major clinical importance for maintaining a healthy life. Sensors are small devices employed for qualitative and quantitative determination of various analytes by monitoring their properties using a certain transduction method. A “real-time” biosensor includes a biological recognition receptor (such as an antibody, enzyme, nucleic acid or whole cell) and a transducer to convert the biological binding event to a detectable signal, which is read out indicating both the presence and concentration of the analyte molecule. A wide range of specific analytes with biomedical significance at ultralow concentration can be sensitively detected. In nano(bio)sensors, nanoparticles (NPs) are incorporated into the (bio)sensor design by attachment to the suitably modified platforms. For this purpose, metal nanoparticles have many advantageous properties making them useful in the transducer component of the (bio)sensors. Gold, silver and platinum NPs have been the most popular ones, each form of these metallic NPs exhibiting special surface and interface features, which significantly improve the biocompatibility and transduction of the (bio)sensor compared to the same process in the absence of these NPs. This comprehensive review is focused on the main types of NPs used for electrochemical (bio)sensors design, especially screen-printed electrodes, with their specific medical application due to their improved analytical performances and miniaturized form. Other advantages such as supporting real-time decision and rapid manipulation are pointed out. A special attention is paid to carbon-based nanomaterials (especially carbon nanotubes and graphene), used by themselves or decorated with metal nanoparticles, with excellent features such as high surface area, excellent conductivity, effective catalytic properties and biocompatibility, which confer to these hybrid nanocomposites a wide biomedical applicability.
format	article
author	Luminita Fritea Florin Banica Traian Octavian Costea Liviu Moldovan Luciana Dobjanschi Mariana Muresan Simona Cavalu
author_facet	Luminita Fritea Florin Banica Traian Octavian Costea Liviu Moldovan Luciana Dobjanschi Mariana Muresan Simona Cavalu
author_sort	Luminita Fritea
title	Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
title_short	Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
title_full	Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
title_fullStr	Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
title_full_unstemmed	Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
title_sort	metal nanoparticles and carbon-based nanomaterials for improved performances of electrochemical (bio)sensors with biomedical applications
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/40f73dadbc774830be930c8b448a760e
work_keys_str_mv	AT luminitafritea metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications AT florinbanica metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications AT traianoctaviancostea metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications AT liviumoldovan metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications AT lucianadobjanschi metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications AT marianamuresan metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications AT simonacavalu metalnanoparticlesandcarbonbasednanomaterialsforimprovedperformancesofelectrochemicalbiosensorswithbiomedicalapplications
_version_	1718431996891365376

Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications

Ejemplares similares