Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain.

Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain.

The analgesic effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as analgesics. In this study, we examine whether this effect is related to nerve injury-induced microglial activation. We the...

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Bibliographic Details
Main Authors: Joanna Mika, Katarzyna Popiolek-Barczyk, Ewelina Rojewska, Wioletta Makuch, Katarzyna Starowicz, Barbara Przewlocka
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/40f9a48929dc4a749c23b846615a1931
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