Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans

Yuhta Nomura and Naoshi Dohmae report the discovery of a small protein-coding gene that overlaps the tumor suppressor gene Scribble. Their data suggest that the overlapping gene, oSCRIB, limits the translation of downstream Scribble and may have important implications in cancer.

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Autores principales: Yuhta Nomura, Naoshi Dohmae
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/40fe3b0a6c8d401fbad9f9c7866d26aa
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spelling oai:doaj.org-article:40fe3b0a6c8d401fbad9f9c7866d26aa2021-12-02T17:24:11ZDiscovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans10.1038/s42003-021-02619-82399-3642https://doaj.org/article/40fe3b0a6c8d401fbad9f9c7866d26aa2021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02619-8https://doaj.org/toc/2399-3642Yuhta Nomura and Naoshi Dohmae report the discovery of a small protein-coding gene that overlaps the tumor suppressor gene Scribble. Their data suggest that the overlapping gene, oSCRIB, limits the translation of downstream Scribble and may have important implications in cancer.Yuhta NomuraNaoshi DohmaeNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Yuhta Nomura
Naoshi Dohmae
Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
description Yuhta Nomura and Naoshi Dohmae report the discovery of a small protein-coding gene that overlaps the tumor suppressor gene Scribble. Their data suggest that the overlapping gene, oSCRIB, limits the translation of downstream Scribble and may have important implications in cancer.
format article
author Yuhta Nomura
Naoshi Dohmae
author_facet Yuhta Nomura
Naoshi Dohmae
author_sort Yuhta Nomura
title Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
title_short Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
title_full Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
title_fullStr Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
title_full_unstemmed Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
title_sort discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene scribble in humans
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/40fe3b0a6c8d401fbad9f9c7866d26aa
work_keys_str_mv AT yuhtanomura discoveryofasmallproteinencodingcisregulatoryoverlappinggeneofthetumorsuppressorgenescribbleinhumans
AT naoshidohmae discoveryofasmallproteinencodingcisregulatoryoverlappinggeneofthetumorsuppressorgenescribbleinhumans
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